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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/53218
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dc.creatorFabiobotelhopt_BR
dc.creatorMarcelo e. Mirandapt_BR
dc.creatorRenan Farias r. Vianapt_BR
dc.creatorSherif Galal s. Emilpt_BR
dc.creatorPramod s. Puligandlapt_BR
dc.creatorVivian Resendept_BR
dc.creatorBernardo a. Campospt_BR
dc.creatorPaulo Custódio Furtado Cruzeiropt_BR
dc.creatorClecio Picarropt_BR
dc.creatorRicardo Paixaopt_BR
dc.date.accessioned2023-05-12T19:36:58Z-
dc.date.available2023-05-12T19:36:58Z-
dc.date.issued2021-
dc.citation.volume233pt_BR
dc.citation.issue5pt_BR
dc.citation.spagee148pt_BR
dc.citation.epagee149pt_BR
dc.identifier.doi10.1016/j.jamcollsurg.2021.08.399pt_BR
dc.identifier.issn10727515pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/53218-
dc.description.resumoINTRODUCTION: The Gastroschisis Prognostic Score (GPS) stratifies patients as high or low-risk based on the visual assessment of intestinal matting, atresia, perforation, or necrosis shortly after birth. Its applicability to low and middle-income settings remains unknown. This study aimed to validate the GPS as a prognostic tool in a public hospital within a middle-income country. METHODS: With REB approval, we conducted a prospective study of all newborns with gastroschisis in a Brazilian neonatal public hospital from 2015-2019. Infants were stratified into low and high-risk cohorts based on the GPS. In addition to basic demographics, data collected included duration of parenteral nutrition (TPN), mechanical ventilation (MV), length of stay (LOS), sepsis, and mortality. Univariate and multivariate analyses were conducted to identify which outcomes the GPS independently predicted.RESULTS: Sixty-one newborns with gastroschisis were treated in our center. The mean birth weight, gestational age, and 5’ Apgar score were 2258g, 36weeks, and 9. Accordingly to the GPS, 24 infants (39.3%) were identified as low-risk and 37 (60.7%) as high-risk. The high-risk group presented with prolonged use of TPN (p<0.001), MV (p<0.001), and LOS (p:0.002). There was no association between GPS with sepsis or mortality in this study. CONCLUSION: This is the first study that validates the GPS as a prognostic tool in a middle-income country. Several important outcome measures were predicted by the GPS allowing for better parental counseling and resource allocation. The GPS is a reliable tool that can be used in various resource settings.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE MORFOLOGIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CIRURGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of the American College of Surgeons-
dc.rightsAcesso Abertopt_BR
dc.subjectGastrosquisept_BR
dc.subjectPaíses em Desenvolvimentopt_BR
dc.subject.otherGastrosquisept_BR
dc.subject.otherPaíses em Desenvolvimentopt_BR
dc.subject.otherBrasilpt_BR
dc.titleGastroschisis prognostic score predicts high-risk newborns with gastroschisis in a middle-income countrypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S1072751521016471pt_BR
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