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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/63873
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dc.creatorGuilherme Augusto de Melo Jardimpt_BR
dc.creatorWillian Xerxes Coelho Oliveirapt_BR
dc.creatorRossimiriam Pereira de Freitaspt_BR
dc.creatorRubem Figueiredo Sadok Menna Barretopt_BR
dc.creatorThaissa Lúcio Silvapt_BR
dc.creatorMarilia Oliveira Fonseca Goulartpt_BR
dc.creatorEufrânio Nunes da Silva Júniorpt_BR
dc.date.accessioned2024-02-08T18:16:46Z-
dc.date.available2024-02-08T18:16:46Z-
dc.date.issued2018-
dc.citation.volume16pt_BR
dc.citation.issue10pt_BR
dc.citation.spage1686pt_BR
dc.citation.epage1691pt_BR
dc.identifier.doihttps://doi.org/10.1039/C8OB00196Kpt_BR
dc.identifier.issn1477-0539pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/63873-
dc.description.resumoWe report a sequential C–H iodination/organoyl-thiolation of naphthoquinones and their relevant trypanocidal activity. Under a combination of AgSR with a copper source, sulfur-substituted benzenoid quinones were prepared in high yields (generally >90%). This provides an efficient and general method for preparing A-ring modified naphthoquinoidal systems, recognized as a challenge in quinone chemistry.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.description.sponsorshipINCT – Instituto nacional de ciência e tecnologia (Antigo Instituto do Milênio)pt_BR
dc.description.sponsorshipFAPERJ - Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiropt_BR
dc.description.sponsorshipOutra Agênciapt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE QUÍMICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofOrganic & Biomolecular Chemistrypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectQuinone chemistrypt_BR
dc.subjectNaphthoquinonespt_BR
dc.subjectTrypanocidal quinonespt_BR
dc.subjectOrganoyl-thiolationpt_BR
dc.subjectIodinationpt_BR
dc.subject.otherQuímica orgânicapt_BR
dc.subject.otherQuinonapt_BR
dc.titleDirect sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinonespt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://pubs.rsc.org/en/content/articlelanding/2018/ob/c8ob00196kpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-9882-3085pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0722-5352pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6974-3724pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1352-0641pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6557-8653pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9860-3667pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-1281-5453pt_BR
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