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http://hdl.handle.net/1843/71012| Type: | Artigo de Periódico |
| Title: | Cross-kingdom microbial interactions in dental implant-related infections: is Candida albicans a new villain? |
| Authors: | Belen Stephanie Retamal-Valdes Jamil Awad Shibli Magda Feres João Gabriel Silva Souza Valentim A. R. Barão Martinna Bertolini Raphael Cavalcante Costa Aline Araújo Sampaio Victória Lopes Abdo Bruna Egumi Nagay Nidia Castro |
| Abstract: | Candida albicans, an oral fungal opportunistic pathogen, has shown the ability to colonize implant surfaces and has been frequently isolated from biofilms associated with dental implant-related infections, possibly due to its synergistic interactions with certain oral bacteria. Moreover, evidence suggests that this cross-kingdom interaction on implant can encourage bacterial growth, leading to increased fungal virulence and mucosal damage. However, the role of Candida in implant-related infections has been overlooked and not widely explored or even considered by most microbiological analyses and therapeutic approaches. Thus, we summarized the scientific evidence regarding the ability of C. albicans to colonize implant surfaces, interact in implant-related polymicrobial biofilms, and its possible role in peri-implant infections as far as biologic plausibility. Next, a systematic review of preclinical and clinical studies was conducted to identify the relevance and the gap in the existing literature regarding the role of C. albicans in the pathogenesis of peri-implant infections. |
| Subject: | Candida albicans Interações Microbianas Implantes Dentários Fungos |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE ODONTOLOGIA SOCIAL E PREVENTIVA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | 10.1016/j.isci.2022.103994 |
| URI: | http://hdl.handle.net/1843/71012 |
| Issue Date: | 15-Apr-2022 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S2589004222002644?via%3Dihub |
| metadata.dc.relation.ispartof: | IScience |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Cross-kingdom microbial interactions in dental implant-related infections is Candida albicans a new villain.pdf | 3.16 MB | Adobe PDF | View/Open |
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