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http://hdl.handle.net/1843/76753
Type: | Artigo de Periódico |
Title: | Synthesis of potential anti-trypanosoma cruzi azole-naftifine analogues by azide-alkyne click reaction |
Authors: | Carlos Henrique Callegario Zacchi Stephanie Souto Maior Federighi Fernanda Ramos Gadelha Felipe Terra Martins Rosemeire Brondi Alves Ângelo de Fátima |
Abstract: | Twenty novel azole-naftifine analogues were obtained using azide–alkyne click reaction. Five of them were more potent than the positive control naftifine revealing an unprecedented antiproliferative effects against Trypanosoma cruzi. |
Subject: | Química Tripanossomo Produtos de ação antimicrobiana |
language: | eng |
metadata.dc.publisher.country: | Brasil |
Publisher: | Universidade Federal de Minas Gerais |
Publisher Initials: | UFMG |
metadata.dc.publisher.department: | ICX - DEPARTAMENTO DE QUÍMICA |
Rights: | Acesso Restrito |
metadata.dc.identifier.doi: | https://doi.org/10.1016/j.mencom.2018.03.029 |
URI: | http://hdl.handle.net/1843/76753 |
Issue Date: | 2018 |
metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0959943618300786 |
metadata.dc.relation.ispartof: | Mendeleev Communications |
Appears in Collections: | Artigo de Periódico |
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