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http://hdl.handle.net/1843/BUOS-8QLLX4| Type: | Dissertação de Mestrado |
| Title: | Imunidade anti-rábica contra diferentes amostras de vírus de rua |
| Authors: | Marilia de Oliveira Cavalieri |
| First Advisor: | Elvio Carlos Moreira |
| First Referee: | Romulo Cerqueira Leite |
| Second Referee: | Zelia Ines Portela Lobato |
| Third Referee: | Jose Ailton da Silva |
| metadata.dc.contributor.referee4: | Anilton Cesar Vasconcelos |
| Abstract: | A imunidade anti-rábica, conferida por vacina inativada tipo Fuenzalida & Palacios e modificada amostra SAD, foi avaliada por desafio com seis amostras de vírus de rua isoladas do homem, cão, bovino, eqüino, suíno e morcego hematófago, em Minas Gerais, em 1993 e 1995. A multiplicação e titulação dos vírus de rua e dos vírus fixo CVS-24 e DR-19 foram realizados em camundongos de 21 dias dc idade. Utilizou-se os testes de Habel e Koprowski, recomendados pela OMS, para testar o grau de proteção conferido pelas vacinas frente ao desafio com vírus de rua e fixo. A proteção conferida pelas vacinas, inativada tipo Fuenzalida & palacios e modificada amostra SAD, foi respectivamente de 70% a 100% e 100%, dc acordo com as amostras de vírus empregadas no desafio. |
| Abstract: | Immunity confered by Fuenzalida & Palacios inactivated vaccine and by attenuated strain SAD was evaluated by challenge with six strains of street rabies virus isolated from man, dog, cattle, horse, pig and bat in Minas Gerais between 1993 and 1995. The multiplication and titration of street virus and fixed virus CVS-24 and DR-19 were studied in mice of 21 days. To evaluate the protection confered by vaccines against a challenge with the street and fixed virus, Habel and Koprowski tests were used. The protection confered by Fuenzalida &. Palacios inactivated vaccine and attenuated strain SAD was respectivelly between 70% and 100% and 100%, according with the virus strains used in challenge. |
| Subject: | Raiva Vacinas Imunidade |
| language: | Português |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| Rights: | Acesso Aberto |
| URI: | http://hdl.handle.net/1843/BUOS-8QLLX4 |
| Issue Date: | 6-Sep-1996 |
| Appears in Collections: | Dissertações de Mestrado |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| disserta__o_de_mestrado_de_mar_lia_de_oliveira_cavalieri.pdf | 811.05 kB | Adobe PDF | View/Open |
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