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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/39792
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Campo DCValorIdioma
dc.creatorLetícia Gonçalves Freitaspt_BR
dc.creatorCristina de Mello Gomide Lourespt_BR
dc.creatorMarcos Vinícius Ferreira Silva Marcospt_BR
dc.creatorFernanda Freire Campos Nunespt_BR
dc.creatorMaria Das Gracas Carvalhopt_BR
dc.creatorLuci Maria SantAna Dussept_BR
dc.date.accessioned2022-03-04T13:39:29Z-
dc.date.available2022-03-04T13:39:29Z-
dc.date.issued2016-
dc.citation.volume6pt_BR
dc.citation.issue6pt_BR
dc.citation.spage320pt_BR
dc.citation.epage328pt_BR
dc.identifier.doihttp://www.ijhsr.org/IJHSR_Vol.6_Issue.6_June2016/52.pdfpt_BR
dc.identifier.issn2249-9571pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/39792-
dc.description.resumoPhysiologically, menstrual cycle is a complex process involving cell replication and growth under the influence of hormones, growth factors, neurotransmitters, regulatory molecules and hemostatic mechanisms. During this process, there is platelet aggregate formation, coagulation cascade activation, synthesis and activation of various procoagulant molecules and fibrin clot formation, aiming to control bleeding. Subsequently, activation of the fibrinolytic system is observed for remodeling the tissue. This review considers articles that evaluated hemostatic and hematological alterations during menstrual cycle in order to better understand this physiological process. There is evidence that menstrual cycle is associated with procoagulant (platelet aggregation, coagulation factors and fibrinolysis inhibitors) and anticoagulant (fibrinolysis system activators) changes. However, data are still conflicting for each phase. Current literature confirms that the most important modifications in hemostasis occur due to the fundamental role of progesterone, although follicular and bleeding phases also take place with a balance between the pro and anticoagulant factors. Additional randomized and well controlled clinical studies are required to clarify thehemostatic changes and its consequences in women health.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational Journal of Health Sciences and Researchpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectMenstrual cyclept_BR
dc.subjectHemostatic modificationspt_BR
dc.subjectMenstruation physiologypt_BR
dc.subject.otherCiclo menstrualpt_BR
dc.subject.otherMenstruaçãopt_BR
dc.subject.otherFenômenos fisiológicospt_BR
dc.titleMenstrual cycle and hemostatic modifications: a reviewpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.52403/ijhsrpt_BR
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