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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/49167
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Campo DCValorIdioma
dc.creatorGiseli Carvalho de Paulapt_BR
dc.creatorAdriano Trajanopt_BR
dc.creatorAna Delia Pinzón-Garcíapt_BR
dc.creatorRubén Dario Sinisterrapt_BR
dc.creatorMaría Esperanza Cortés Segurapt_BR
dc.date.accessioned2023-01-26T17:04:31Z-
dc.date.available2023-01-26T17:04:31Z-
dc.date.issued2020-11-01-
dc.citation.volume11pt_BR
dc.citation.issue11pt_BR
dc.citation.spage5484pt_BR
dc.citation.epage5496pt_BR
dc.identifier.doi10.13040/IJPSR.0975-8232.11(11).5484-96.pt_BR
dc.identifier.issn09758232pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/49167-
dc.description.resumoZinc oxide-magnesium has been used in dentistry with limitations especially related to its high acidity and low biocompatibility. The objective of this study was to develop cement based on nano-hydroxyapatite (nHA), chitosan as more biocompatibility agents to increase zinc oxide-magnesium cito-compatibility. The formulations prepared were: 1. Complete cement (HCP) with nHA, zinc oxide-magnesium, and chitosan; 2. cement without nHA (CP); 3. Without chitosan (HP); 4. Without zinc oxide-magnesium (HC), and CPZn as control. All cement were compared for setting times, solubility, contact angle, pH, calcium ion release, shear strength, the thermogravimetry analysis, X-ray diffraction, Raman spectroscopy, 3T3-L1 fibroblasts cell compatibility, and antimicrobial activity. The results showed that HCP cement had setting time (mean ± S.D) of 5.5 ± 0.18 min, (p≥0.05) and neutral pH values on 14 days, calcium release of 10 mgL-1, and solubility with a value of 2.15%. The physicochemical characterization showed an expected pattern from the raw materials and composition. The values of the contact angle measurements indicated increased wettability for the HCP than the control cement. The zinc oxide-magnesium presence was important to improve the mechanical strength. HCP and HC cement had similar fibroblast compatibility and significantly higher than the others (p≤ 0.05). The experimental cement showed antimicrobial activity against P.g, F.n, A.a, and S.aon the diffusion agar test higher than control cement (17.6 ± 1.1 mm) p≤ 0.05. These studies indicated that this cement showed appropriate physicochemical properties with high cytocompatibility, maintaining its resistance and antimicrobial action, suggesting be beneficial in dentistrypt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational Journal of Pharmaceutical Science and Researchpt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherCement industrypt_BR
dc.subject.otherChitosanpt_BR
dc.titleIncreased properties and citocompatibility of zinc oxide-magnesium cementpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://ijpsr.com/bft-article/increased-properties-and-citocompatibility-of-zinc-oxide-magnesium-cement/pt_BR
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