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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/49370
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Campo DCValorIdioma
dc.creatorMichele Macedo Moraespt_BR
dc.creatorPatrícia da Conceição Rocha Rabelopt_BR
dc.creatorValéria Andrade Pintopt_BR
dc.creatorWashington Pirespt_BR
dc.creatorSamuel Penna Wannerpt_BR
dc.creatorRaphael Escorsim Szawkapt_BR
dc.creatorDanusa Dias Soarespt_BR
dc.date.accessioned2023-02-01T14:58:36Z-
dc.date.available2023-02-01T14:58:36Z-
dc.date.issued2018-04-
dc.citation.volume673pt_BR
dc.citation.spage73pt_BR
dc.citation.epage78pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.neulet.2018.02.058pt_BR
dc.identifier.issn0304-3940pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/49370-
dc.description.resumoListening to melodic music is regarded as a non-pharmacological intervention that ameliorates various disease symptoms, likely by changing the activity of brain monoaminergic systems. Here, we investigated the effects of exposure to melodic music on the concentrations of dopamine (DA), serotonin (5-HT) and their respective metabolites in the caudate-putamen (CPu) and nucleus accumbens (NAcc), areas linked to reward and motor control. Male adult Wistar rats were randomly assigned to a control group or a group exposed to music. The music group was submitted to 8 music sessions [Mozart’s sonata for two pianos (K. 488) at an average sound pressure of 65 dB]. The control rats were handled in the same way but were not exposed to music. Immediately after the last exposure or control session, the rats were euthanized, and their brains were quickly removed to analyze the concentrations of 5-HT, DA, 5-hydroxyindoleacetic acid (5-HIAA) and 3,4-dihydroxyphenylacetic acid (DOPAC) in the CPu and NAcc. Auditory stimuli affected the monoaminergic system in these two brain structures. In the CPu, auditory stimuli increased the concentrations of DA and 5-HIAA but did not change the DOPAC or 5-HT levels. In the NAcc, music markedly increased the DOPAC/DA ratio, suggesting an increase in DA turnover. Our data indicate that auditory stimuli, such as exposure to melodic music, increase DA levels and the release of 5-HT in the CPu as well as DA turnover in the NAcc, suggesting that the music had a direct impact on monoamine activity in these brain areas.pt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentEEF - DEPARTAMENTO DE EDUCAÇÃO FÍSICApt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofNeuroscience Letterspt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectCaudate-putamenpt_BR
dc.subjectDopaminept_BR
dc.subjectMonoaminespt_BR
dc.subjectMusicpt_BR
dc.subjectNucleus accumbenspt_BR
dc.subjectSerotoninpt_BR
dc.subject.otherGânglios da basept_BR
dc.subject.otherDopaminapt_BR
dc.subject.otherAminaspt_BR
dc.subject.otherMúsicapt_BR
dc.subject.otherCérebro - Localização das funçõespt_BR
dc.subject.otherSerotoninapt_BR
dc.titleAuditory stimulation by exposure to melodic music increases dopamine and serotonin activities in rat forebrain areas linked to reward and motor controlpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0304394018301460?via%3Dihubpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-4707-6099pt_BR
dc.identifier.orcidhttp://orcid.org/0000-0002-7313-6553pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3140-510Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4659-1032pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-2639-3469pt_BR
dc.identifier.orcidhttp://orcid.org/0000-0002-5705-8890pt_BR
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