1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/53118
Registro completo de metadatos
Campo DCValorIdioma
dc.creatorC. P. Galvãopt_BR
dc.creatorM. Tinanopt_BR
dc.creatorLetícia Paiva Francopt_BR
dc.creatorC. M. F. F. Naderpt_BR
dc.creatorA. E. Fernandespt_BR
dc.creatorHelena Maria Gonçalves Beckerpt_BR
dc.date.accessioned2023-05-11T19:16:15Z-
dc.date.available2023-05-11T19:16:15Z-
dc.date.issued2019-
dc.citation.volume64pt_BR
dc.citation.spageS123pt_BR
dc.citation.epageS123pt_BR
dc.identifier.doi10.1016/j.sleep.2019.11.338pt_BR
dc.identifier.issn13899457pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/53118-
dc.description.resumoIntroduction: Obstructive sleep apnea syndrome in childhood has aroused great interest due to its cardiovascular repercussions and its adverse effects on the quality of life of the affected individuals. However, fundamental aspects of the syndrome remain unknown. Objective: Herein we prospectively assessed pulmonary artery systolic pressure (PASP) and nasal flow in children with obstructive oral breathing with an indication for adenoidectomy and/or tonsillectomy and their relation- ship to the obstructive apnea and hypopnea index (OAHI). Materials and methods: Twenty-one children were evaluated at the time of the surgical indication (T0) and 18 months later (T1). Polysomnography, and rhinomanometry data were collected when we evaluated PASP. Results: Among the 21 children, 13 (61.9%) presented an altered OAHI at T0. Fourteen children (66.7%) un- derwent surgery. Of these, nine (64.3%) had an altered OAHI at T0 and seven (50.0%) at T1. Of the seven non- operated children, four (57.1%) had an altered OAHI at T0 and two (33.3%) at T1. Mean nasal flow increased in both groups independently of surgery (p<- 0.001). PASP exhibited a significant reduction between T0 and T1 in the operated group (p ,- 0.001). OAHI of the operated group did not show a significant decrease over time (p ¼ 0.074). In the non-operated children, the average nasal flow increased (p < 0.001), the PASP values did not reduce (p ¼ 0.99), and the OAHI increased and then decreased over time (p ¼ 0.025). Discussion: The present study stands out for the inclusion of a study group composed of children who did not undergo surgical treatment. It also included a lengthy follow-up (18 months) that allowed for a thorough investigation of OAHI changes over time. Indeed, the follow-up prac- ticed herein was much longer than those of previous studies (maximum of 7 months). The change in cardiovascular parameters after surgery indicates signs of early cardiovascular dysfunction in patients with OSA. It is not yet known whether these early alterations will be reflected in the future cardiovascular morbidity. We found that, in contrast to the findings regarding the operated patients, the OAHI of the non-operated group tended to normalize and PASP levels remain stable (p ¼ 0.99). These findings must be taken with caution given the small sample size of the non-operated group. It is not known whether elevated blood pressure levels in child- hood, even within normal limits, may contribute to future cardiovascular morbidity. Knowledge of the progression and the factors involved in the pathophysiology of OSA is important to identify the appropriate time to intervene and to determine which patients can benefit from the intervention. Isolated adenotonsillectomy, contrary to what was previously thought, is often insufficient to achieve complete resolution of sleep breathing problems and normalization of OAHI. Conclusion: PASP decreased significantly and OAHI did not normalize in the operated group. Mean nasal airflow increased in the operated and nonoperated groups.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofSleep Medicine-
dc.rightsAcesso Restritopt_BR
dc.subjectApneia Obstrutiva do Sonopt_BR
dc.subjectCriançapt_BR
dc.subjectAdenoidectomiapt_BR
dc.subject.otherApneia Obstrutiva do Sonopt_BR
dc.subject.otherCriançapt_BR
dc.subject.otherAdenoidectomiapt_BR
dc.titleProspective evaluation of obstructive sleep apnea syndrome, nasal flow and systolic pressure of the pulmonary artery in children with tonsillar hypertrophypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S1389945719306999pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0479-4621pt_BR
Aparece en las colecciones:Artigo de Periódico

archivos asociados a este elemento:
no existem archivos asociados a este elemento.
Mostrar registro simple del elemento Visualizar estadísticas


Los elementos en el repositorio están protegidos por copyright, con todos los derechos reservados, salvo cuando es indicado lo contrario.