Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/55700
Type: Artigo de Periódico
Title: Infection surveillance in pediatric hematopoietic stem cell transplantation recipients
Authors: Daniela Caldasteixeira
Lilian Martins Oliveira Diniz
Paulo Henrique Orlandi Mourão
Fabiana Maria Kakehasi
Antonio Vaz de Macedo
Helena Duani
Wanessa Trindade Clemente
Karla Emília de sá Rodrigues
Roberta Maia de Castro Romanelli
Abstract: Objective: To describe the profile of reported healthcare- associated infections (HAIs) in pediatric patients submitted to hematopoietic stem cell transplantation (HSCT) at a reference center.Methods: Retrospective cohort of pediatric patients who were submitted to HSCT from 2008 to 2016. The criteria for HAI were based on those established by the National Healthcare Safety Network. Data were collected by active surveillance per formed daily by professionals. This study was approved by the institutional research ethics committee. Results: A total of 86 HSCTs were performed in 81 patients younger than 18 years of age (median, 10 years). Of these, 69 (85%) were males. Aplastic anemia and leukemia were the main diagnoses. A total of 140 HAIs were diagnosed with an incidence density of 28.2 infections/1000 patient- days. The most common HAI was laboratory confirmed bloodstream infection (46), the majority of which was reported to be central venous catheter- associated (43). Gram- negative bacteria were the most prevalent mi croorganisms (58.5%). Almost all the infections occurred until 30 days after transplan tation, and 17 deaths were observed within 180 days after the procedure. Conclusion: Active surveillance of HAIs in HSCT children allowed the evaluation of the incidence and profile of HAIs, which is essential for the health care of these patients.
Subject: Transplante de Medula Óssea
Hematologia
Transplante de Células-Tronco Hematopoéticas
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: MED - DEPARTAMENTO DE CLÍNICA MÉDICA
MED - DEPARTAMENTO DE PEDIATRIA
Rights: Acesso Restrito
metadata.dc.identifier.doi: 10.1111/ejh.12982
URI: http://hdl.handle.net/1843/55700
Issue Date: 2017
metadata.dc.url.externa: https://onlinelibrary.wiley.com/doi/10.1111/ejh.12982
metadata.dc.relation.ispartof: European Journal of Haematology
Appears in Collections:Artigo de Periódico

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