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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/56498
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Campo DCValorIdioma
dc.creatorSalvina Mariade Campos-carlipt_BR
dc.creatorAntônio Lúcio Teixeirapt_BR
dc.creatorAline Silva Mirandapt_BR
dc.creatorIngrid Caroline Silva Diaspt_BR
dc.creatorAmanda de Oliveirapt_BR
dc.creatorBreno Fiuza Cruzpt_BR
dc.creatorÉrica Leandro Marciano Vieirapt_BR
dc.creatorNatalia Pessoa Rochapt_BR
dc.creatorIzabela Guimarães Barbosapt_BR
dc.creatorJoão Vinícius Salgadopt_BR
dc.date.accessioned2023-07-17T20:24:14Z-
dc.date.available2023-07-17T20:24:14Z-
dc.date.issued2017-
dc.citation.volume74pt_BR
dc.citation.issue2017pt_BR
dc.citation.spage96pt_BR
dc.citation.epage101pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.comppsych.2017.01.008pt_BR
dc.identifier.issn0010440Xpt_BR
dc.identifier.urihttp://hdl.handle.net/1843/56498-
dc.description.resumoObjective: Changes in immune system have been reported in schizophrenia. This study aimed to evaluate the involvement of IL-33, a member of the IL-1 cytokine family, in schizophrenia and its association with cognitive performance in these patients.Methods: Forty patients with chronic schizophrenia and 40 healthy subjects participated in the study. Serum levels of IL-33 and sST2(soluble form of the IL-33 receptor) were measured using enzyme-linked immunosorbent assay (ELISA). Patients were evaluated with the Brief Assessment of Cognition in Schizophrenia (BACS) and the Schizophrenia Cognition Rating Scale (SCoRS). Results: Patients with schizophrenia and controls presented similar serum levels of IL-33 and sST2. Levels of both markers were positively correlated with cognitive performance in patients with schizophrenia. Conclusion: We found a significant correlation between IL-33 and sST2 levels and cognition in schizophrenia. Our results might help in the understanding of how immune markers are associated with cognitive impairment in schizophrenia. It remains to be determined whether the association between IL-33/sST2 and cognition is restricted to patients with schizophrenia.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE FARMACOLOGIApt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE MORFOLOGIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE SAÚDE MENTALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofComprehensive Psychiatry-
dc.rightsAcesso Restritopt_BR
dc.subjectSchizophreniapt_BR
dc.subjectInterleukin-33pt_BR
dc.subjectCognitive performancept_BR
dc.subject.otherEsquizofreniapt_BR
dc.subject.otherInterleucina-33pt_BR
dc.subject.otherTestes Neuropsicológicospt_BR
dc.titleSerum levels of interleukin-33 and its soluble form receptor (sst2) are associated with cognitive performance in patients with schizophreniapt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0010440X16304874?via%3Dihubpt_BR
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