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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/56526
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dc.creatorNayara Felicidade Tomazbrazpt_BR
dc.creatorNatalia Pessoa Rochapt_BR
dc.creatorÉrica Leandro Marciano Vieirapt_BR
dc.creatorIzabela Guimarães Barbosapt_BR
dc.creatorRodrigo Santiago Gomezpt_BR
dc.creatorAdriana Maria Kakehasipt_BR
dc.creatorAntonio Lucio Teixeirapt_BR
dc.date.accessioned2023-07-17T21:26:05Z-
dc.date.available2023-07-17T21:26:05Z-
dc.date.issued2018-01-05-
dc.citation.volume50pt_BR
dc.citation.spage41pt_BR
dc.citation.epage44pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.jocn.2018.01.011pt_BR
dc.identifier.issn09675868pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/56526-
dc.description.resumoMyasthenia gravis (MG) is a neuromuscular autoimmune disease characterized by skeletal muscle weakness which can impact motor function and, furthermore, produce negative impact on the health-related quality of life (HRQOL). Objective: To evaluate the predictors for HRQOL in patients with MG. Methods: Eighty patients were evaluated with the MG Foundation of America classification and the MG Composite scale. HRQOL was estimated by the MGQOL15, while anxious and depressive symptoms were evaluated with the Hospital Anxiety and Depression Scale (HAD). Results: The mean age of patients was 41.9 years with mean illness duration of 13.5 years. Almost half of the patients (43.75%) had significant anxiety and more than a quarter (27.50%) had depressive symptoms. Factors that influenced the HRQOL in MG were skeletal muscle weakness and anxiety and depressive symptoms (p < .001 in logistic regres sion model). Conclusion: Anxiety and depressive symptoms, besides motor symptoms, influence HRQOL inMG. Mental health must be a clinical focus in addition to the treatment of somatic symptoms during the course of MG.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTORpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE SAÚDE MENTALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Clinical Neuroscience-
dc.rightsAcesso Restritopt_BR
dc.subjectMyasthenia gravispt_BR
dc.subjectHealth-related quality of lifept_BR
dc.subjectAnxietypt_BR
dc.subjectDepressionpt_BR
dc.subjectMuscle weaknesspt_BR
dc.subject.otherMiastenia Gravispt_BR
dc.subject.otherQualidade de Vidapt_BR
dc.subject.otherAnsiedadept_BR
dc.subject.otherDepressãopt_BR
dc.subject.otherDebilidade Muscularpt_BR
dc.titleMuscle strength and psychiatric symptoms influence health-related quality of life in patients with myasthenia gravispt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0967586817312274?via%3Dihubpt_BR
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