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http://hdl.handle.net/1843/56741| Type: | Artigo de Periódico |
| Title: | Brain Temperature in Spontaneously Hypertensive Rats during Physical Exercise in Temperate and Warm Environments |
| Authors: | Lucas Rios Drummond Ana Cançado Kunstetter Filipe Ferreira Vaz Helton Oliveira Campos André Gustavo Pereira de Andrade Cândido Celso Coimbra Antônio José Natali Samuel Penna Wanner Thales Nicolau Prímola Gomes |
| Abstract: | This study aimed to evaluate brain temperature (Tbrain) changes in spontaneously hypertensive rats (SHRs) subjected to two different physical exercise protocols in temperate or warm environments. We also investigated whether hypertension affects the kinetics of exercise-induced increases in Tbrain relative to the kinetics of abdominal temperature (Tabd) increases. Male 16-week-old normotensive Wistar rats (NWRs) and SHRs were implanted with an abdominal temperature sensor and a guide cannula in the frontal cortex to enable the insertion of a thermistor to measure Tbrain. Next, the animals were subjected to incremental-speed (initial speed of 10 m/min; speed was increased by 1 m/min every 3 min) or constant-speed (60% of the maximum speed) treadmill running until they were fatigued in a temperate (25°C) or warm (32°C) environment. Tbrain, Tabd and tail skin temperature were measured every min throughout the exercise trials. During incremental and constant exercise at 25°C and 32°C, the SHR group exhibited greater increases in Tbrain and Tabd relative to the NWR group. Irrespective of the environment, the heat loss threshold was attained at higher temperatures (either Tbrain or Tabd) in the SHRs. Moreover, the brain-abdominal temperature differential was lower at 32°C in the SHRs than in the NWRs during treadmill running. Overall, we conclude that SHRs exhibit enhanced brain hyperthermia during exercise and that hypertension influences the kinetics of the Tbrain relative to the Tabd increases, particularly during exercise in a warm environment. |
| Subject: | Temperatura Cérebro Abdome agudo Exercícios físicos |
| language: | por |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | EEF - DEPARTAMENTO DE EDUCAÇÃO FÍSICA EEF - DEPARTAMENTO DE ESPORTES ICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | https://doi.org/10.1371/journal.pone.0155919 |
| URI: | http://hdl.handle.net/1843/56741 |
| Issue Date: | 2016 |
| metadata.dc.url.externa: | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155919 |
| metadata.dc.relation.ispartof: | PLOS ONE |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Brain Temperature in Spontaneously Hypertensive Rats during Physical Exercise in Temperate and Warm Environments.pdf | 1.06 MB | Adobe PDF | View/Open |
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