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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57555
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dc.creatorAna Carolina Pelliciolipt_BR
dc.creatorVinicius Coelho Carrardpt_BR
dc.creatorAlan Roger dos Santos Silvapt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorRodrigo Neves Silvapt_BR
dc.creatorLuiz Alcino Monteiro Gueirospt_BR
dc.creatorOslei Paes de Almeidapt_BR
dc.creatorPablo Agustin Vargaspt_BR
dc.creatorMárcio Ajudarte Lopespt_BR
dc.creatorHélder Antônio Rebelo Pontespt_BR
dc.creatorManoela Domingues Martinspt_BR
dc.date.accessioned2023-08-07T18:18:53Z-
dc.date.available2023-08-07T18:18:53Z-
dc.date.issued2017-
dc.citation.volume123pt_BR
dc.citation.issue4pt_BR
dc.citation.spage477pt_BR
dc.citation.epage481pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2016.12.014pt_BR
dc.identifier.issn2212-4403pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57555-
dc.description.resumoObjectives The aim of this study was to characterize the histomorphometric features of subgemmal neurogenous plaques (SNPs) to better understand their relationship to surrounding microanatomy included in the tissue biopsy samples of the tongue. Study Design A 12-year retrospective study on the files of 3 oral pathology centers yielded 28 SNPs. Hematoxylin and eosin–stained sections were used for histologic analysis, and immunohistochemical staining for S100 protein was performed to better characterize the neural structures. Slides were scanned and histomorphometric analysis carried out using ImageScope software. Results Twenty-one women (75%) and 6 men (21.4%) comprised the sample (mean age 46.4 and 49 years, respectively). Twenty cases (71.4%) were juxtaposed to the tongue epithelium and 16 cases (57.1%) were associated with lymphoid tissue. The mean area of the SNPs was 0.160 mm2, and the mean distance to the overlying epithelium was 0.312 mm. Conclusions SNPs are normal neural structures located on the posterior border of the tongue that represent a non-neoplastic regional anatomic variation. In some cases, signs or symptoms may be present, and further investigation should be performed. Pathologists should be aware of this entity to avoid confusion with neural lesions.pt_BR
dc.languageporpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA SOCIAL E PREVENTIVApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofOral Surgery, Oral Medicine, Oral Pathology and Oral Radiologypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectTissue biopsypt_BR
dc.subjectTonguept_BR
dc.subjectOral pathologypt_BR
dc.subjectPathologistspt_BR
dc.subject.otherBiópsiapt_BR
dc.subject.otherLínguapt_BR
dc.subject.otherPatologia bucalpt_BR
dc.titleHistomorphometric characterization of subgemmal neurogenous plaquespt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S2212440317300019pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1624-0178pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-2040-6617pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6657-4547pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-4979-4318pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-2002-8003pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-1840-4911pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6677-0065pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7609-8804pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-8662-5965pt_BR
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