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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/57580
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Campo DCValorIdioma
dc.creatorMarco Túlio Gualberto Cintrapt_BR
dc.creatorNilton Alves de Rezendept_BR
dc.creatorMaria Aparecida Camargos Bicalhopt_BR
dc.creatorRafaela Ávilapt_BR
dc.creatorThayana Oliveira Soarespt_BR
dc.creatorLuciana Cristina Matos Cunhapt_BR
dc.creatorKatia Daniela Silveirapt_BR
dc.creatorEdgar Nunes Moraespt_BR
dc.creatorKaique Roger Simaspt_BR
dc.creatorRenato Bragança Fernandespt_BR
dc.creatorDenise Utsch Gonçalvespt_BR
dc.date.accessioned2023-08-07T20:49:59Z-
dc.date.available2023-08-07T20:49:59Z-
dc.date.issued2018-
dc.citation.volume33pt_BR
dc.citation.issue2pt_BR
dc.citation.spagee221pt_BR
dc.citation.epagee227pt_BR
dc.identifier.doihttps://doi.org/10.1002/gps.4773pt_BR
dc.identifier.issn0885-6230pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57580-
dc.description.resumoObjective: To compare the results of neuropsychological tests, evoked potentials N200 andP300 and polymorphisms of ApoE and BDNF rs6265 between patients with normal cognition and those with mild cognitive impairment (MCI) and Alzheimer's dementia (AD). Methods: This is a cross‐sectional study of elderly individuals with normal cognition and those with MCI and AD, who were submitted to evoked potential tests (N200 and P300) by means of hearing stimuli based on the auditory oddball paradigm. Genotyping was obtained by using the real‐time PCR technique.Results: Sixty‐five patients were evaluated as follows: 14 controls, 34 with MCI and 17 with AD. N200 latency and P300 latency and amplitude were not associated with MCI and AD diagnosis. Patients with cognitive impairment (MCI or AD) showed increase in the latencies of P300 and N200. BNDF gene was not associated with cognitive impairment.Conclusion: Latencies of N200 and P300 increased in cognitively impaired patients with the presence of ApoE ε‐4 allele.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational Journal of Geriatric Psychiatry-
dc.rightsAcesso Restritopt_BR
dc.subjectAlzheimer' s diseasept_BR
dc.subjectApolipoproteins Ept_BR
dc.subjectAuditory evoked potentialspt_BR
dc.subjectBrain-Derived Neurotrophic Factorpt_BR
dc.subjectMild cognitive impairmentpt_BR
dc.subject.otherDoença de Alzheimerpt_BR
dc.subject.otherApolipoproteínas Ept_BR
dc.subject.otherPotenciais Evocados Auditivospt_BR
dc.subject.otherFator Neurotrófico Derivado do Encéfalopt_BR
dc.subject.otherDisfunção Cognitivapt_BR
dc.titleIncreased N200 and P300 latencies in cognitively impaired elderly carrying ApoE ε-4 allelept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/journal/10991166pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3089-655Xpt_BR
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