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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/57630
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Campo DCValorIdioma
dc.creatorMarcia Mendonça Carneiropt_BR
dc.creatorRívia Mara Lamaitapt_BR
dc.creatorMárcia Cristina França Ferreirapt_BR
dc.creatorAgnaldo Lopes Silva-Filhopt_BR
dc.date.accessioned2023-08-08T22:42:33Z-
dc.date.available2023-08-08T22:42:33Z-
dc.date.issued2016-09-01-
dc.citation.volume20pt_BR
dc.citation.issue4pt_BR
dc.citation.spage232pt_BR
dc.citation.epage239pt_BR
dc.identifier.doihttps://10.5935/1518-0557.20160045pt_BR
dc.identifier.issn1518-0557pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57630-
dc.description.resumoAlmost 5% of women with endometrial cancer are under age 40, and they often have well-differentiated en dometrioid estrogen-dependent tumors. Cancer survival rates have improved over the last decades so strategies to avoid or reduce the reproductive damage caused by oncologic treatment are needed. We reviewed the published literature to find evidence to answer the following questions: How should we manage women in reproductive age with endometrial cancer? How safe is fertility preservation in endometrial cancer? Can pregnancy influence endometrial cancer recurrence? What are the fertility sparing op tions available? Progestins may be prescribed after careful evaluation and counseling. Suitable patients should be se lected using imaging methods and endometrial sampling since surgical staging will not be performed. Conservative treatment should only be offered to patients with grade 1 well-differentiated tumors, absence of lymph vascular space invasion, no evidence of myometrial invasion, met astatic disease or suspicious adnexal masses, and expres sion of progesterone receptors in the endometrium. The presence of co-existing ovarian metastatic of synchronous cancer should be investigated and ruled out before the de cision to preserve the ovaries. The availability of Assisted Reproductive Technology (ART) has made it possible for women with endometrial cancer to give birth to a child without compromising their prognoses. Gamete, embryo or ovarian tissue cryopreservation techniques can be employed, although the latter remains experimental. Unfortu nately, fertility preservation is rarely considered. Current recommendations for conservative management are based on the overall favorable prognosis of grade 1 minimally invasive tumors. Selected patients with endometrial cancer may be candidates to a safe fertility-preserving management.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE GINECOLOGIA OBSTETRÍCIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJBRA Assisted Reproduction-
dc.rightsAcesso Abertopt_BR
dc.subjectAssisted reproductive technologypt_BR
dc.subjectCancer of the endometriumpt_BR
dc.subjectFemale infertilitypt_BR
dc.subjectReproductive endocrinologypt_BR
dc.subject.otherTécnicas de Reprodução Assistidapt_BR
dc.subject.otherNeoplasias do Endométriopt_BR
dc.subject.otherInfertilidade Femininapt_BR
dc.titleFertility-preservation in endometrial cancer: is it safe? Review of the literaturept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.jbra.com.br/trab/pub/detalhe_trabalho.phppt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-9389-3316pt_BR
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