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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/60394
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dc.creatorAna Valesca Fernandes Gilsonsilvapt_BR
dc.creatorAdriano Neves Coelhopt_BR
dc.creatorJúlia Maria Saraiva Duartept_BR
dc.creatorAugusto Viana da Rochapt_BR
dc.creatorLuiz Gonzaga Paula de Almeidapt_BR
dc.creatorJoão Locke Ferreira de Araújopt_BR
dc.creatorHilton Soares de Oliveirapt_BR
dc.creatorNova Jersey Cláudio de Oliveirapt_BR
dc.creatorCamila Zolinipt_BR
dc.creatorJôsy Hubner de Sousapt_BR
dc.creatorElizângela Gonçalves de Souzapt_BR
dc.creatorDiego Menezespt_BR
dc.creatorRafael Marques de Souzapt_BR
dc.creatorLuciana de Lima Ferreirapt_BR
dc.creatorAlexandra Lehmkuhl Gerberpt_BR
dc.creatorAna Paula de Campos Guimarãespt_BR
dc.creatorPaulo Henrique Silva Maiapt_BR
dc.creatorFernanda Martins Marimpt_BR
dc.creatorLucyene Miguitapt_BR
dc.creatorCristiane Campos Monteiropt_BR
dc.creatorTuffi Saliba Netopt_BR
dc.creatorFabrícia Soares Freire Pugêdopt_BR
dc.creatorFilipe Romero Rebello Moreirapt_BR
dc.creatorDaniel Costa Queirozpt_BR
dc.creatorDamares Nigia Alborguetti Cuzzuol Queirozpt_BR
dc.creatorLuciana Cunha Resende-Moreirapt_BR
dc.creatorFranciele Martins Santospt_BR
dc.creatorErika Fernanda Carlos Souzapt_BR
dc.creatorCarolina Moreira Volochpt_BR
dc.creatorAna Tereza Vasconcelospt_BR
dc.creatorRenato Santana de Aguiarpt_BR
dc.creatorRenan Pedra de Souzapt_BR
dc.creatorOctávio Alcântara Torrespt_BR
dc.creatorPaula Luize Camargos Fonsecapt_BR
dc.creatorRennan Garcias Moreirapt_BR
dc.creatorHugo José Alvespt_BR
dc.creatorVivian Ribeiro Alvespt_BR
dc.creatorTânia Maria de Resende Amaralpt_BR
dc.date.accessioned2023-10-31T21:33:38Z-
dc.date.available2023-10-31T21:33:38Z-
dc.date.issued2022-
dc.citation.volume13pt_BR
dc.citation.spage799713pt_BR
dc.citation.epage12pt_BR
dc.identifier.doihttps://doi.org/10.3389/fmicb.2022.799713pt_BR
dc.identifier.issn1664-302Xpt_BR
dc.identifier.urihttp://hdl.handle.net/1843/60394-
dc.description.resumoThe COVID-19 pandemic has created an unprecedented need for epidemiological monitoring using diverse strategies. We conducted a project combining prevalence, seroprevalence, and genomic surveillance approaches to describe the initial pandemic stages in Betim City, Brazil. We collected 3239 subjects in a population-based age-, sex- and neighborhood-stratified, household, prospective; cross-sectional study divided into three surveys 21 days apart sampling the same geographical area. In the first survey, overall prevalence (participants positive in serological or molecular tests) reached 0.46% (90% CI 0.12–0.80%), followed by 2.69% (90% CI 1.88–3.49%) in the second survey and 6.67% (90% CI 5.42–7.92%) in the third. The underreporting reached 11, 19.6, and 20.4 times in each survey. We observed increased odds to test positive in females compared to males (OR 1.88 95% CI 1.25–2.82), while the single best predictor for positivity was ageusia/anosmia (OR 8.12, 95% CI 4.72–13.98). Thirty-five SARS-CoV-2 genomes were sequenced, of which 18 were classified as lineage B.1.1.28, while 17 were B.1.1.33. Multiple independent viral introductions were observed. Integration of multiple epidemiological strategies was able to adequately describe COVID-19 dispersion in the city. Presented results have helped local government authorities to guide pandemic management.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipFINEP - Financiadora de Estudos e Projetos, Financiadora de Estudos e Projetospt_BR
dc.description.sponsorshipFAPERJ - Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiropt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE BOTÂNICApt_BR
dc.publisher.departmentICB - INSTITUTO DE CIÊNCIAS BIOLOGICASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofFrontiers in Microbiologypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCOVID-19pt_BR
dc.subjectSARS-CoV-2pt_BR
dc.subjectGenomaspt_BR
dc.subjectPandemiapt_BR
dc.subject.otherCOVID-19pt_BR
dc.subject.otherSARS-CoV-2pt_BR
dc.subject.otherGenomaspt_BR
dc.subject.otherPandemiapt_BR
dc.titleSeroprevalence, Prevalence, and Genomic Surveillance: Monitoring the Initial Phases of the SARS-CoV-2 Pandemic in Betim, Brazilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.frontiersin.org/articles/10.3389/fmicb.2022.799713/fullpt_BR
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