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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/61266
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dc.creatorAna Luiza Oliveira Corrêa Rozapt_BR
dc.creatorRicardo Alves Mesquitapt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorAline Corrêa Abrahãopt_BR
dc.creatorMichelle Agostinipt_BR
dc.creatorBruno Augusto Benevenuto de Andradept_BR
dc.creatorEricka Janine Dantas da Silveirapt_BR
dc.creatorRené Martínez-Florespt_BR
dc.creatorBenjamin Martínez Rondanellipt_BR
dc.creatorJavier Alberdi-Navarropt_BR
dc.creatorLiam Robinsonpt_BR
dc.creatorEmanuel Mendes Sousapt_BR
dc.creatorConstanza Marinpt_BR
dc.creatorJosé Narciso Rosa Assunçãopt_BR
dc.creatorRenato Valiatipt_BR
dc.creatorEduardo Rodrigues Fregnanipt_BR
dc.creatorAlan Roger Santos-Silvapt_BR
dc.creatorMarcio Ajudarte Lopespt_BR
dc.creatorKeith Hunterpt_BR
dc.creatorSyed Ali Khurrampt_BR
dc.creatorPaul Speightpt_BR
dc.creatorAdalberto Mosqueda-Taylorpt_BR
dc.creatorAmanda Almeida Leitept_BR
dc.creatorWillie Van Herdeenpt_BR
dc.creatorRomán Carlospt_BR
dc.creatorJohn Wrightpt_BR
dc.creatorOslei Paes de Almeidapt_BR
dc.creatorMário José Romañachpt_BR
dc.creatorPablo Agustin Vargaspt_BR
dc.creatorGleyson Kleber do Amaral-Silvapt_BR
dc.creatorThayná Melo de Lima Moraispt_BR
dc.creatorVivian Petersen Wagnerpt_BR
dc.creatorLauren Frenzel Schuchpt_BR
dc.creatorAna Carolina Uchoa Vasconcelospt_BR
dc.creatorJosé Alcides Almeida de Arrudapt_BR
dc.date.accessioned2023-11-22T19:38:42Z-
dc.date.available2023-11-22T19:38:42Z-
dc.date.issued2021-05-
dc.citation.volume131pt_BR
dc.citation.issue5pt_BR
dc.citation.spage549pt_BR
dc.citation.epage557pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2020.08.022pt_BR
dc.identifier.issn22124403pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/61266-
dc.description.resumoObjective: The aim of this study was to report the clinicopathologic features of 62 cases of central odontogenic fibroma (COdF). Study design: Clinical and radiographic data were collected from the records of 13 oral pathology laboratories. All cases were microscopically reviewed, considering the current World Health Organization classification of tumors and were classified according to histopathologic features. Results: There were 43 females and 19 males (average age 33.9 years; range 8-63 years). Clinically, COdF lesions appeared as asymptomatic swellings, occurring similarly in the maxilla (n = 33) and the mandible (n = 29); 9 cases exhibited palatal depression. Imaging revealed well-defined, interradicular unilocular (n = 27), and multilocular (n = 12) radiolucencies, with displacement of contiguous teeth (55%) and root resorption (46.4%). Microscopically, classic features of epithelial-rich (n = 33), amyloid (n = 10), associated giant cell lesion (n = 7), ossifying (n = 6), epithelial-poor (n = 3), and granular cell (n = 3) variants were seen. Langerhans cells were highlighted by CD1a staining in 17 cases. Most patients underwent conservative surgical treatments, with 1 patient experiencing recurrence. Conclusions: To the best of our knowledge, this study represents the largest clinicopathologic study of COdF. Most cases appeared as locally aggressive lesions located in tooth-bearing areas in middle-aged women. Inactive-appearing odontogenic epithelium is usually observed within a fibrous/fibromyxoid stroma, occasionally exhibiting amyloid deposits, multinucleated giant cells, or granular cells.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofOral Surgery Oral Medicine Oral Pathology Oral Radiologypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectacesso restrito Central odontogenic fibroma: an international multicentric study of 62 cases fao clinica assunto fibroma dia 23 do10 2023 proxima busca 5 felipe paiva fonsecapt_BR
dc.subjecttítulo periódico Oral surgery oral medicine oral pathology oral radiologypt_BR
dc.subject.otherFibromapt_BR
dc.subject.otherRadiographypt_BR
dc.subject.otherAmyloidpt_BR
dc.subject.otherStudy characteristicspt_BR
dc.subject.otherPathologypt_BR
dc.titleCentral odontogenic fibroma: an international multicentric study of 62 casespt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S2212440320311718?via%3Dihubpt_BR
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