1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/61649
Full metadata record
DC FieldValueLanguage
dc.creatorHugo José Alvespt_BR
dc.creatorWalyson Coelho Costapt_BR
dc.creatorJaqueline Silva de Oliveirapt_BR
dc.creatorEva Lídia Arcoverde Medeirospt_BR
dc.creatorCarolina Senra Alves de Souzapt_BR
dc.creatorJuliana Wilke Salibapt_BR
dc.creatorAndré Luiz Menezespt_BR
dc.creatorEneida Santos de Oliveirapt_BR
dc.creatorTalita Emile Ribeiro Adelinopt_BR
dc.creatorNatalia Rocha Guimaraespt_BR
dc.creatorAdriana Aparecida Ribeiropt_BR
dc.creatorJoão Locke Ferreira de Araújopt_BR
dc.creatorRennan Garcias Moreirapt_BR
dc.creatorDanielle Alves Gomes Zaulipt_BR
dc.creatorJoice do Prado Silvapt_BR
dc.creatorFrederico Scott Varella Maltapt_BR
dc.creatorAlessandro Clayton de Souza Ferreirapt_BR
dc.creatorAna Valesca Fernandes Gilson Silvapt_BR
dc.creatorPoliane Alfenas-zerbinipt_BR
dc.creatorFlavia Oliveira de Souzapt_BR
dc.creatorAdriano de Paula Sabinopt_BR
dc.creatorLaura do Amaral Xavierpt_BR
dc.creatorPaula Luize Camargos Fonsecapt_BR
dc.creatorNatália Virtude Carobinpt_BR
dc.creatorAlex Fiorini de Carvalhopt_BR
dc.creatorKarine Lima Lourençopt_BR
dc.creatorSantuza Maria Ribeiro Teixeirapt_BR
dc.creatorAna Paula Salles Moura Fernandespt_BR
dc.creatorFlavio Guimarães da Fonsecapt_BR
dc.creatorJônatas Santos Abrahãopt_BR
dc.creatorFelipe Campos de Melo Ianipt_BR
dc.creatorRodrigo Araújo Lima Rodriguespt_BR
dc.creatorRenan Pedra de Souzapt_BR
dc.creatorFilipe Romero Rebello Moreirapt_BR
dc.creatorRenato Santana Aguiarpt_BR
dc.creatorDiego Menezes Bonfimpt_BR
dc.creatorDaniel Costa Queirozpt_BR
dc.creatorLucyene Miguitapt_BR
dc.creatorRafael Marques de Souzapt_BR
dc.creatorVictor Emmanuel Viana Geddespt_BR
dc.date.accessioned2023-12-01T21:08:56Z-
dc.date.available2023-12-01T21:08:56Z-
dc.date.issued2022-12-09-
dc.citation.volume14pt_BR
dc.citation.issue12pt_BR
dc.citation.spage2747pt_BR
dc.citation.epage15pt_BR
dc.identifier.doihttps://doi.org/10.3390/v14122747pt_BR
dc.identifier.issn1999-4915pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/61649-
dc.description.resumoSince its first identification in Brazil, the variant of concern (VOC) Gamma has been associated with increased infection and transmission rates, hospitalizations, and deaths. Minas Gerais (MG), the second-largest populated Brazilian state with more than 20 million inhabitants, observed a peak of cases and deaths in March–April 2021. We conducted a surveillance study in 1240 COVID-19-positive samples from 305 municipalities distributed across MG’s 28 Regional Health Units (RHU) between 1 March to 27 April 2021. The most common variant was the VOC Gamma (71.2%), followed by the variant of interest (VOI) zeta (12.4%) and VOC alpha (9.6%). Although the predominance of Gamma was found in most of the RHUs, clusters of Zeta and Alpha variants were observed. One Alpha-clustered RHU has a history of high human mobility from countries with Alpha predominance. Other less frequent lineages, such as P.4, P.5, and P.7, were also identified. With our genomic characterization approach, we estimated the introduction of Gamma on 7 January 2021, at RHU Belo Horizonte. Differences in mortality between the Zeta, Gamma and Alpha variants were not observed. We reinforce the importance of vaccination programs to prevent severe cases and deaths during transmission peaks.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.description.sponsorshipFINEP - Financiadora de Estudos e Projetos, Financiadora de Estudos e Projetospt_BR
dc.description.sponsorshipFAPERJ - Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiropt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIALpt_BR
dc.publisher.departmentFARMACIA - FACULDADE DE FARMACIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofVirusespt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectPhylodinamicspt_BR
dc.subjectPCR-genotypingpt_BR
dc.subjectSARS-CoV-2 spreadpt_BR
dc.subjectGenome sequencingpt_BR
dc.subjectVariantspt_BR
dc.subject.otherSARS-CoV-2pt_BR
dc.subject.otherCOVID-19pt_BR
dc.subject.otherGenomaspt_BR
dc.titleMonitoring the Establishment of VOC Gamma in Minas Gerais, Brazil: A Retrospective Epidemiological and Genomic Surveillance Studypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.mdpi.com/1999-4915/14/12/2747pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9469-9673pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8103-9235pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-9603-455Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6607-8818pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6863-7970pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4178-0387pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-0358-6161pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
File Description SizeFormat 
Monitoring the Establishment of VOC Gamma in Minas Gerais, Brazil_ A Retrospective Epidemiological and Genomic Surveillance Study.pdf2.09 MBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.