Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/62178
Type: Artigo de Periódico
Title: Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
Authors: Lívia Pereira Horta
Yane Campolina Cachuite Mota
Gisele Maria Barbosa
Taniris Cafiero Braga
Ivanildo Evódio Marriel
Ângelo de Fátima
Luzia Valentina Modolo
Abstract: The plant phenolic natural products (PNPs) protocatechuic aldehyde, syringaldehyde and vanillin were used as platforms for obtaining four urease inhibitors. Urea (urease substrate) or thiourea (urease inhibitor) core was added to the structure of newly synthesized compounds to provide inhibitors up to 230-fold more active than the PNPs they originated from. The PNP derivatives are mixed inhibitors with higher affinity to urease active site. Two compounds were as efficient as N-(butyl)thiophosphoric triamide (NBPT) toward soil. Overall, PNPs derivatives are promising urease inhibitors for use as additive in urea-based fertilizers formulations.
Subject: Ureia como fertilizante
Química
Produtos naturais
Fenóis
Inibidores - Urease
Aldeídos
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: ICB - DEPARTAMENTO DE BOTÂNICA
ICX - DEPARTAMENTO DE QUÍMICA
Rights: Acesso Aberto
metadata.dc.identifier.doi: https://doi.org/10.21577/0103-5053.20160208
URI: http://hdl.handle.net/1843/62178
Issue Date: 2016
metadata.dc.url.externa: https://www.scielo.br/j/jbchs/a/yjZC8mqjtfrtj7styVFfXnb/
metadata.dc.relation.ispartof: Journal of the Brazilian Chemical Society
Appears in Collections:Artigo de Periódico

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