1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/62531
Registro completo de metadatos
Campo DCValorIdioma
dc.creatorHenrique Silveira Costapt_BR
dc.creatorMárcia Maria Oliveira Limapt_BR
dc.creatorFábio Silva Martins da Costapt_BR
dc.creatorAna Thereza Chavespt_BR
dc.creatorMaria Carmo Pereira Nunespt_BR
dc.creatorPedro Henrique Scheidt Figueiredopt_BR
dc.creatorManoel Otávio da Costa Rochapt_BR
dc.date.accessioned2024-01-09T22:43:29Z-
dc.date.available2024-01-09T22:43:29Z-
dc.date.issued2018-
dc.citation.volume51pt_BR
dc.citation.issue4pt_BR
dc.citation.spage421pt_BR
dc.citation.epage426pt_BR
dc.identifier.doi10.1590/0037-8682-0158-2018pt_BR
dc.identifier.issn00378682pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/62531-
dc.description.resumoin which functional impairment is detectable remains uncertain. The present study compared functional capacity between healthy controls and patients with different clinical forms of Chagas disease. A systematic review and meta-analysis (PROSPERO database CRD42017058353) was conducted following a search of the MEDLINE, Web of Science, CINAHL, and LILACS databases from September to December 2017 for articles published in English, Spanish, or Portuguese, with no date restrictions. We included studies that compared the VO2peak between healthy and Chagas disease patients, stratified according to 3 clinical forms [no apparent cardiac disease, non-dilated Chagas heart disease (CHD), and dilated CHD]. Seven cross-sectional studies were included. Chagas disease patients without apparent cardiac disease (n=208) had VO2 peak values [mean difference, -1.55ml/kg/min; 95% confidence interval (CI), -4.98ml/kg/min to 1.88ml/kg/min] similar to those of healthy controls (n=105; p=0.38, I2=52%). In non-dilated CHD (n=159), VO2peak was 8.71ml/kg/min lower (95% CI, -13.99 to -3.42ml/kg/min) than in healthy controls (n=59; p=0.001, I2=75%). VO2 peak was also significantly lower (mean difference, -9.30ml/kg/min; 95% CI, -11.34 to -7.25ml/kg/min) in dilated CHD patients (n=131) than in healthy controls (n=53; p<0.001, I2=0%). Exercise capacity in Chagas disease patients without apparent cardiac disease is similar to that in healthy controls. Functional impairment in Chagas disease is detectable in the early stages of cardiac involvement, even in the absence of systolic dysfunction and signs of heart failure.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical-
dc.rightsAcesso Abertopt_BR
dc.subjectChagas diseasept_BR
dc.subjectFunctional Residual Capacitypt_BR
dc.subjectExercise Testpt_BR
dc.subjectSystematic Reviewpt_BR
dc.subject.otherChagas diseasept_BR
dc.subject.otherFunctional Residual Capacitypt_BR
dc.subject.otherExercise Testpt_BR
dc.subject.otherSystematic Reviewpt_BR
dc.titleReduced functional capacity in patients with chagas disease: a systematic review with meta-analysispt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/0037-8682-0158-2018pt_BR
Aparece en las colecciones:Artigo de Periódico

archivos asociados a este elemento:
archivo Descripción TamañoFormato 
Reduced functional capacity in patients with Chagas disease pdfa.pdf543.22 kBAdobe PDFVisualizar/Abrir
Mostrar registro simple del elemento Visualizar estadísticas


Los elementos en el repositorio están protegidos por copyright, con todos los derechos reservados, salvo cuando es indicado lo contrario.