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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/62979
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dc.creatorRose Mary Ferreira Lisboa da Silvapt_BR
dc.creatorCarlos Eduardo Souza Mirandapt_BR
dc.creatorMaira Tonidandel Barbosapt_BR
dc.creatorMaria Aparecida Camargos Bicalhopt_BR
dc.date.accessioned2024-01-17T19:01:37Z-
dc.date.available2024-01-17T19:01:37Z-
dc.date.issued2018-
dc.citation.volume110pt_BR
dc.citation.issue4pt_BR
dc.citation.spage303pt_BR
dc.citation.epage311pt_BR
dc.identifier.doi10.5935/abc.20180043pt_BR
dc.identifier.issn0066782Xpt_BR
dc.identifier.urihttp://hdl.handle.net/1843/62979-
dc.description.resumoBackground: The prevalence of orthostatic hypotension (OH) increases with age and is associated with changes in autonomic regulation of blood pressure (BP) and heart rate (HR).Objective: to assess HR and HR variability (HRV) in elderly subjects with OH and determine OH predictors.Methods: a total of 105 patients aged ≥ 60 years, 39 with OH (case group) and 66 without OH (control group) (age-matched) were studied. Patients underwent clinical assessment, electrocardiogram, biochemistry tests and Holter monitoring for spectral analysis of HRV (Fourier transform) in the supine and orthostatism positions to identify low frequency (LF) and high frequency (HF) components, as well as the LF/HF ratio.Results: median age was 73.0 years, 64 patients were women. In all participants, there was a reduction in HF (133.0versus 76.0 ms2, p = 0.001) and increase in LF/HF (1.6 vs 2.1; p < 0.001) and no change in LF (233.0 versus 218.0 ms2,p = 0.080). Between-group comparisons revealed significant differences in the median values of HR in the supine position (62.0 vs. 69.0 bpm, p = 0.001) and LF in the supine position (157.0 in case group vs. 275.0 ms2 in the control group, p = 0.014). Spearman’s correlation coefficient of 0.27 was found between the groups. Multivariate analysis revealed that HR in the supine position was an independent variable for OH (p = 0.001- 95%CI = -0.022 and -0.006). Using the operating characteristic curve, the best cutoff point was 61 bpm, with a sensitivity of 77.3% and specificity of 51.3%, positive predictive value of 61.3%, and negative predictive value 69.3%. Odds ratio was 3.23 for OH in patients with a HR lower than 61 bpm.Conclusions: lower LF and HR in the supine position were found in patients with OH, regardless of age and gender. The independent predictor for OH was HR in the supine position, with an odds ratio of 3.23 for values lower than 61 bpm.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofArquivos Brasileiros de Cardiologia-
dc.rightsAcesso Abertopt_BR
dc.subjectHeart Ratept_BR
dc.subjectHypotension, Orthostaticpt_BR
dc.subjectAccidental Fallspt_BR
dc.subjectSyncopept_BR
dc.subjectAgedpt_BR
dc.subjectDizzinesspt_BR
dc.subject.otherHeart Ratept_BR
dc.subject.otherHypotension, Orthostaticpt_BR
dc.subject.otherAccidental Fallspt_BR
dc.subject.otherSyncopept_BR
dc.subject.otherAgedpt_BR
dc.subject.otherDizzinesspt_BR
dc.titleHeart rate and its variability by spectral analysis in elderly patients with orthostatic hypotension: case-control studypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.5935/abc.20180043pt_BR
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