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Type:	Artigo de Periódico
Title:	Association between periodontitis and serum c-reactive protein levels
Authors:	Rafael Paschoal Esteves Lima Christian Santiago Reis Francisco Santirocchi Júnior Lucas Guimarães Abreu Fernando de Oliveira Costa
Abstract:	Background: Periodontal disease may be associated with more bacteria and consequent induction of a systemic inflammatory process, with changes in the levels of C-reactive protein (CRP). The purpose of this cross-sectional study was to evaluate the association between periodontitis and serum levels of C-reactive protein. Material and methods: The sample comprised 100 individuals distributed into two groups according to serum levels of C-reactive protein: normal or altered. Social, biological and behavioral data were collected by means of a structured questionnaire. Additionally, a blood test was requested to measure C-reactive protein levels. CRP values less than 3 mg/l were considered normal. Periodontal clinical examination was conducted in each participant for analysis of probing depth, bleeding on probing and clinical attachment level. Descriptive statistics, univariate analysis and logistic regression were performed. Results were provided in odds ratio, confidence intervals and p values. Results: Individuals with altered C-reactive protein levels showed a higher prevalence of periodontitis than individuals with normal C-reactive protein levels (p=0.008). In the final logistic regression model, individuals with periodontitis were more likely to present altered C-reactive protein than individuals without periodontitis (OR=3.27, CI=1.42-7.52, p=0.005). Conclusions: The alteration of the C-reactive protein levels among individuals with a higher prevalence of periodontitis corroborates clinical evidence that periodontal infection has a systemic impact.
Subject:	C-reactive protein Periodontitis Cytokines Periodontal diseases
language:	eng
metadata.dc.publisher.country:	Brasil
Publisher:	Universidade Federal de Minas Gerais
Publisher Initials:	UFMG
metadata.dc.publisher.department:	FAO - DEPARTAMENTO DE CLÍNICA FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
Rights:	Acesso Aberto
metadata.dc.identifier.doi:	https://doi.org/10.4317%2Fjced.57041
URI:	http://hdl.handle.net/1843/69172
Issue Date:	1-Sep-2020
metadata.dc.url.externa:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511054/
metadata.dc.relation.ispartof:	Journal of Clinical and Experimental Dentistry
Appears in Collections:	Artigo de Periódico

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