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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/75951
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Campo DCValorIdioma
dc.creatorMaria Cássia Ferreira de Aguiarpt_BR
dc.creatorMariana Saturnino de Noronhapt_BR
dc.creatorRoger Lanes Silveirapt_BR
dc.creatorJosé Augusto Dias Araújopt_BR
dc.creatorFlavio Sirihal Werkemapt_BR
dc.creatorDiana Bellpt_BR
dc.creatorPatrícia Carlos Caldeirapt_BR
dc.date.accessioned2024-09-04T21:17:58Z-
dc.date.available2024-09-04T21:17:58Z-
dc.date.issued2020-
dc.citation.volume130 Oral surgery oral medicine oral pathology oral radiology assunto Immunohistochemistry fao clínicapt_BR
dc.citation.issue5pt_BR
dc.citation.spagee308pt_BR
dc.citation.epagee315pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2020.01.004pt_BR
dc.identifier.issn2212-4411pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/75951-
dc.description.resumoObjectives: Epithelioid rhabdomyosarcoma (EpiRMS) is a novel morphologically distinct variant of rhabdomyosarcoma, with an unusually challenging microscopic diagnosis. The occurrence of rhabdomyosarcomas in the jaws is extremely rare. This study presents the first case of EpiRMS in the jaw (mandible) and a literature review of the previous 35 cases of EpiRMS. Study design: Here, we report a case of EpiRMS affecting an 18-year-old male patient. Clinical, imaging, microscopic, and immunohistochemical features are discussed and previously reported cases of EpiRMS are reviewed. Results: An 18-year-old male patient presented with an exophytic sessile growth on the buccal gingiva, and orthopantomography revealed irregular bone loss. Microscopic analysis showed a large number of cells with epithelioid appearance. Immunohistochemistry staining was positive for desmin, myogenin, MyoD1, smooth muscle actin, h-caldesmon, INI-1, and AE1-AE3. The patient's disease was staged as T4aN1M0 and was treated with surgical excision combined with chemotherapy. Conclusions: The occurrence of RMS in the mandible is rare, and this is the first case of EpiRMS in the jaw. EpiRMS is an unusual histologic subtype that mimics other sarcomas and epithelial malignancies, making diagnosis a challenge. A specific immunohistochemistry panel aids in the diagnosis. EpiRMS has an aggressive course and an unfavorable prognosis.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofOral Surgery Oral Medicine Oral Pathology Oral Radiologypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectdpt_BR
dc.subject.otherReviewpt_BR
dc.subject.otherMandiblept_BR
dc.subject.otherMaxillapt_BR
dc.subject.otherEpitheliumpt_BR
dc.subject.otherRhabdomyosarcomapt_BR
dc.subject.otherImmunohistochemistrypt_BR
dc.subject.otherExcision repairpt_BR
dc.subject.otherDrug therapypt_BR
dc.subject.otherDiagnosispt_BR
dc.titleEpithelioid rhabdomyosarcoma: report of the first case in the jawpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S2212440320300183?via%3Dihubpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9273-376Xpt_BR
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