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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/77991
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Campo DCValorIdioma
dc.creatorGiovanna Ribeiro Soutopt_BR
dc.creatorLaiz Fernandes Mendes Nunespt_BR
dc.creatorBarbara Brandão Tanurept_BR
dc.creatorRicardo Santiago Gomezpt_BR
dc.creatorRicardo Alves de Mesquitapt_BR
dc.date.accessioned2024-11-12T19:18:56Z-
dc.date.available2024-11-12T19:18:56Z-
dc.date.issued2016-
dc.citation.volume121pt_BR
dc.citation.issue6pt_BR
dc.citation.spage651pt_BR
dc.citation.epage656pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2016.02.009pt_BR
dc.identifier.issn2212-4411pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/77991-
dc.description.resumoObjective: To evaluate and compare the number of CD1a+ dendritic cells (DCs) in oral lichen planus (OLP), amalgam lichenoid reaction (ALR), and normal oral mucosa (NOM). Study design: Fourteen cases of OLP and ALR, diagnosed both clinically and histologically, were obtained from an archive of an oral pathology service. Seven specimens of NOM were collected and served as controls. Immunohistochemistry was used to identify CD1a+ DCs. Densities were calculated using specimens of epithelium and lamina propria. For OLP and ALR, specimens of lamina propria included cells from inflammatory infiltrate (region A), and from below inflammatory infiltrate (region B). Comparisons and statistical analyses were performed among OLP, ALR, and NOM. Results: A higher density of CD1a+ DCs was observed in OLP compared to ALR in region A (P < .05) and regions A+B (P < .05). A higher density of CD1a+ DCs was also observed in OLP compared with NOM in the regions A+B (P < .05). Statistically significant differences were not observed for analyses involving epithelial tissue. Conclusions: The observation that there is a lower quantity of DCs in ALR specimens compared with specimens from individuals with OLP suggests that the role for DCs in the 2 diseases may be different. The difference in cell density could be used in the differential diagnosis of these 2 diseases, but the overlapping intervals in the statistical analysis may limit the application of this approach in surgical practice.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofOral Surgery, Oral Medicine, Oral Pathology and Oral Radiologypt_BR
dc.rightsAcesso Restritopt_BR
dc.subject.otherCell Countpt_BR
dc.subject.otherDendritic cellspt_BR
dc.subject.otherLichen planus, oralpt_BR
dc.subject.otherMouth mucosapt_BR
dc.subject.otherImmunohistochemistrypt_BR
dc.subject.otherDiagnosispt_BR
dc.subject.otherEvaluation studypt_BR
dc.titleCD1a+ dendritic cells in oral lichen planus and amalgam lichenoid reactionpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S2212440316000687?via%3Dihubpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3617-8794pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-8770-8009pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3207-4007pt_BR
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