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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/79476
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Campo DCValorIdioma
dc.creatorBárbara Chaves Santospt_BR
dc.creatorAna Luisa Ferreira Fonsecapt_BR
dc.creatorLívia Garcia Ferreirapt_BR
dc.creatorHelem Sena Ribeiropt_BR
dc.creatorMaria Isabel Toulson Davisson Correiapt_BR
dc.creatorAgnaldo Soares Limapt_BR
dc.creatorFrancisco Guilherme Cancela e Pennapt_BR
dc.creatorLucilene Rezende Anastáciopt_BR
dc.date.accessioned2025-01-24T18:45:09Z-
dc.date.available2025-01-24T18:45:09Z-
dc.date.issued2022-01-
dc.citation.volume41pt_BR
dc.citation.issue1pt_BR
dc.citation.spage97pt_BR
dc.citation.epage104pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.clnu.2021.11.008pt_BR
dc.identifier.issn02615614pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/79476-
dc.description.resumoBackground & aims Studies using the Global Leadership Initiative on Malnutrition (GLIM) criteria for patients with liver cirrhosis are limited. This study aimed to assess the impact of malnutrition according to the GLIM criteria on the outcomes of patients awaiting a liver transplant (LTx) and compare these criteria with Subjective Global Assessment (SGA). Methods This retrospective observational study included adult patients awaiting LTx. Patient clinical data, nutritional status according to various tools including SGA, and resting energy expenditure were assessed. The distinct phenotypic and etiologic criteria provided 36 different GLIM combinations. The GLIM criteria and SGA were compared using the kappa coefficient. The variables associated with mortality before and after the LTx and with a longer length of stay (LOS) after LTx (≥18 days) were assessed by Cox regression and logistic regression analyses, respectively. Results A total of 152 patients were included [median age 52.0 (interquartile range: 46.5–59.5) years; 66.4% men; 63.2% malnourished according to SGA]. The prevalence of malnutrition according to the GLIM criteria ranged from 0.7% to 30.9%. The majority of the GLIM combinations exhibited poor agreement with SGA. Independent predictors of mortality before and after LTx were presence of ascites or edema (p = 0.011; HR:2.58; CI95%:1.24–5.36), GLIM 32 (PA-phase angle + MELD) (p = 0.026; HR:2.08; CI95%:1.09–3.97), GLIM 33 (PA + MELD-Na ≥ 12) (p = 0.018; HR:2.17; CI95%:1.14–4.13), and GLIM 34 (PA + Child–Pugh) (p = 0.043; HR:1.96; CI95%:1.02–3.77). Malnutrition according to GLIM 28 (handgrip strength + Child-Pugh) was independently associated with a longer LOS (p = 0.029; OR:7.21; CI95%:1.22–42.50). Conclusion The majority of GLIM combinations had poor agreement with SGA, and 4 of the 36 GLIM combinations were independently associated with adverse outcomes.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOSpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CIRURGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofClinical Nutritionpt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectCirrosept_BR
dc.subjectTransplante de fígadopt_BR
dc.subjectDesnutriçãopt_BR
dc.subjectMortalidadept_BR
dc.subject.otherPacientespt_BR
dc.subject.otherTransplantept_BR
dc.subject.otherFígadopt_BR
dc.subject.otherDesnutriçãopt_BR
dc.titleDifferent combinations of the GLIM criteria for patients awaiting a liver transplant: poor performance for malnutrition diagnosis but a potentially useful prognostic toolpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/abs/pii/S0261561421005094pt_BR
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