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Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/79496
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Campo DCValorIdioma
dc.creatorFernanda Bispo Nunespt_BR
dc.creatorMaria Sissa Pereira Sant'anapt_BR
dc.creatorAndré Myller Barbosa Silvapt_BR
dc.creatorMichelle Agostinipt_BR
dc.creatorNathalie Henriques Silva Canedopt_BR
dc.creatorBruno Augusto Benevenuto de Andradept_BR
dc.creatorMário José Romañachpt_BR
dc.creatorDavi Lavareda Corrêapt_BR
dc.creatorRamiro Alejandro Tomasipt_BR
dc.creatorRaghu Radhakrishnanpt_BR
dc.creatorRicardo Santiago Gomezpt_BR
dc.creatorSilvia Ferreira de Sousapt_BR
dc.creatorPeter A. Brennanpt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.date.accessioned2025-01-27T16:15:25Z-
dc.date.available2025-01-27T16:15:25Z-
dc.date.issued2020-01-
dc.citation.volume49pt_BR
dc.citation.issue1pt_BR
dc.citation.spage14pt_BR
dc.citation.epage20pt_BR
dc.identifier.doihttps://doi.org/10.1111/jop.12953pt_BR
dc.identifier.issn1600-0714pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/79496-
dc.description.resumoBackground: Solitary fibrous tumour is an unusual neoplasm of the oral cavity that is sometimes not clinically distinguishable from other lesions. The purpose of the present study was to review the clinical, microscopic and molecular aspects of malignant and benign solitary fibrous tumour of the oral cavity currently available in literature. Methods: For our review, an electronic search was performed using PubMed, Scopus, Ovid/MedLine, Web of science and ProQuest Dissertations and Theses Global database. Results: A total of 74 publications reporting 150 cases were included. Oral solitary fibrous tumours are most frequently described as submucosal, well-circumscribed, asymptomatic nodule, more prevalent in females in their fourth to fifth decades of life. Buccal mucosa is the most commonly affected site by the benign tumour variant, whereas the tongue is the most common location affected by the malignant form of the neoplasm. Most of the lesions were treated by conservative surgery. One recurrent malignant tumour and one metastasis are reported. Conclusion: Asymptomatic normal-coloured submucosal nodules located in the buccal mucosa and tongue in adult patients are suggestive of oral solitary fibrous tumour, but only a careful microscopic examination can differentiate benign from malignant variants and the use of immunohistochemistry (CD34, Bcl-2, CD99 and STAT6), and cytogenetic studies (NAB2-STAT6) contribute significantly to confirm the diagnosis of solitary fibrous tumour in difficult cases.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - FACULDADE DE ODONTOLOGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Oral Pathology & Medicinept_BR
dc.rightsAcesso Restritopt_BR
dc.subjectNAB2-STAT6pt_BR
dc.subjectSTAT6pt_BR
dc.subjectHemangiopericytomapt_BR
dc.subjectOral cavitypt_BR
dc.subjectSolitary fibrous tumourpt_BR
dc.subject.otherHemangiopericytomapt_BR
dc.subject.otherMouthpt_BR
dc.subject.otherMicroscopypt_BR
dc.subject.otherImmunohistochemistrypt_BR
dc.subject.otherClinical studypt_BR
dc.subject.otherMouth mucosapt_BR
dc.subject.otherTonguept_BR
dc.subject.otherNeoplasmspt_BR
dc.subject.otherSurgical oncologypt_BR
dc.titleSolitary fibrous tumour of the oral cavity: an updatept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.12953pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0088-4777pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-8770-8009pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-7820-4749pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-4804-3264pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6657-4547pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-0199-1884pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9524-4638pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-3648-337Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-3259-606Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7853-5916pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-7378-4086pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-2705-8221pt_BR
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