Use este identificador para citar o ir al link de este elemento:
http://hdl.handle.net/1843/81625| Tipo: | Artigo de Periódico |
| Título: | Significance of chemokine and chemokine receptors in head and neck squamous cell carcinoma: a critical review |
| Autor(es): | Janine Mayra da Silva Danilo Figueiredo Soave Tálita Pollyanna Moreira dos Santos Aline Carvalho Batista Remo Castro Russo Mauro Martins Teixeira Tarcília Aparecida da Silva |
| Resumen: | Chemokines are small chemotactic proteins that coordinate circulation of immune/inflammatory cells throughout body compartments. Because of this property chemokines and their cell surface receptors are implicated in several physiological and pathological conditions, including cancer. These molecules are expressed by neoplastic or stromal cells and have effects at tumor primary site (e.g. stimulating angiogenesis and tumor cells motility) and lymph nodes (creating a gradient to direct migration of neoplastic cells). In this article we review the current knowledge about the function(s) of chemokines and receptors in squamous cell carcinoma from the oral cavity and head and neck region. Accumulating evidence suggests some chemokine(s) and receptor(s) as potential targets in adjuvant therapies for these malignancies. |
| Asunto: | Chemokines Inflammation Squamous cell carcinoma of head and neck Angiogenesis Cell movement |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Institución: | UFMG |
| Departamento: | FAO - DEPARTAMENTO DE CLÍNICA ICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIA ICB - DEPARTAMENTO DE FARMACOLOGIA ICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICA ICB - DEPARTAMENTO DE MORFOLOGIA |
| Tipo de acceso: | Acesso Restrito |
| Identificador DOI: | https://doi.org/10.1016/j.oraloncology.2016.02.016 |
| URI: | http://hdl.handle.net/1843/81625 |
| Fecha del documento: | may-2016 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S1368837516000464?via%3Dihub |
| metadata.dc.relation.ispartof: | Oral oncology |
| Aparece en las colecciones: | Artigo de Periódico |
archivos asociados a este elemento:
no existem archivos asociados a este elemento.
Los elementos en el repositorio están protegidos por copyright, con todos los derechos reservados, salvo cuando es indicado lo contrario.