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  3. Artigo de Periódico
Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/81666
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Campo DCValorIdioma
dc.creatorJôice Dias Corrêapt_BR
dc.creatorAdriana Machado Saraivapt_BR
dc.creatorCelso Martins Queiroz-Juniorpt_BR
dc.creatorMila Fernandes Moreira Madeirapt_BR
dc.creatorPoliana Mendes Duartept_BR
dc.creatorMauro Martins Teixeirapt_BR
dc.creatorDanielle Glória Souzapt_BR
dc.creatorTarcília Aparecida da Silvapt_BR
dc.date.accessioned2025-04-16T16:33:09Z-
dc.date.available2025-04-16T16:33:09Z-
dc.date.issued2016-06-
dc.citation.volume39pt_BR
dc.citation.spage91pt_BR
dc.citation.epage96pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.anaerobe.2016.03.006pt_BR
dc.identifier.issn1095-8274pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/81666-
dc.description.resumoRheumatoid arthritis (RA) and periodontitis (PD) are chronic inflammatory disorders that cause bone loss. PD tends to be more prevalent and severe in RA patients. Previous experimental studies demonstrated that RA triggers alveolar bone loss similarly to PD. The aim of this study was to investigate if arthritis-induced alveolar bone loss is associated with modification in the oral microbiota. Checkerboard DNA-DNA hybridization was employed to analyze forty oral bacterial species in 3 groups of C57BL/6 mice: control (n = 12; without any challenge); Y4 (n = 8; received oral inoculation of Aggregatibacter Actinomycetemcomitans strain FDC Y4) and AIA group (n = 12; chronic antigen-induced arthritis). The results showed that AIA and Y4 group exhibited similar patterns of bone loss. The AIA group exhibited higher counts of most bacterial species analyzed with predominance of Gram-negative species similarly to infection-induced PD. Prevotella nigrescens and Treponema denticola were detected only in the Y4 group whereas Campylobacter showae, Streptococcus mitis and Streptococcus oralis were only found in the AIA group. Counts of Parvimonas micra, Selenomonas Noxia and Veillonella parvula were greater in the AIA group whereas Actinomyces viscosus and Neisseira mucosa were in large proportion in Y4 group. In conclusion, AIA is associated with changes in the composition of the oral microbiota, which might account for the alveolar bone loss observed in AIA mice.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIApt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE FARMACOLOGIApt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE MICROBIOLOGIApt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE MORFOLOGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofAnaerobept_BR
dc.rightsAcesso Restritopt_BR
dc.subjectArthritispt_BR
dc.subjectMicrobiotapt_BR
dc.subjectPeriodontal diseasept_BR
dc.subject.otherArthritispt_BR
dc.subject.otherMicrobiotapt_BR
dc.subject.otherPeriodontal diseasespt_BR
dc.subject.otherAlveolar bone losspt_BR
dc.subject.otherBacteriapt_BR
dc.titleArthritis-induced alveolar bone loss is associated with changes in the composition of oral microbiotapt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/abs/pii/S1075996416300208?via%3Dihubpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0170-6163pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7884-7709pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1770-9978pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6944-3008pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9623-7835pt_BR
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