Diabetes and impaired fasting glucose in a population-based sample of individuals aged 75 + years: associations with cognition, major depressive disorder, functionality and quality of life—the Pietà study
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Universidade Federal de Minas Gerais
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Objectives To investigate the rates of diabetes mellitus (DM) and impaired fasting glucose (IFG) in a population-based sample of
individuals aged 75 + years old and their associations with cognitive performance, depression, functionality, and quality of life
(QoL).Study design Overall, 350 people participated in the study. Assessments of cognition, mood, functionality and QoL were performed using the mini-mental state examination (MMSE), clock-drawing, category fluency tests, the Mini-International
Neuropsychiatric Interview, Pfeffer’s Functional Activities Questionnaire, and the WHO Quality of Life-Old (WHOQOL-OLD).
Results IFG (ADA criteria) was identified in 42.1% of the sample, while the DM rate was 24.1%. Lack of knowledge of the DM
diagnosis and lack of treatment occurred in 27% and 39% of the sample, respectively. Rates of dementia and depression, MMSE,
category fluency scores, and previous cardiovascular events did not differ between the glycaemic groups. Individuals with DM
performed worse on the clock-drawing test, functionality, and WHOQOL-OLD than the other participants. Individuals with IFG
presented similar QoL and functionality when compared with the group without DM. Conclusions IFG and DM were common in this population-based sample aged 75 + years old, as were inadequate diagnoses and treatments of DM. DM individuals presented poor performance in the executive function test, functionality, and QoL. Further studies are recommended to investigate the value of an IFG diagnosis among the most elderly population.
Abstract
Assunto
Neuropatias Diabéticas, Demência, Idoso Fragilizado, Qualidade de vida
Palavras-chave
Diabetes, Dementia, Impaired fasting glucose, Functionality, Older adult, Quality of life
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https://link.springer.com/article/10.1007/s10072-020-05008-x