Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/40060
Type: Artigo de Periódico
Title: Revisiting the chronic renal disease in pediatric patients
Authors: Rívia Mara Morais e Silva
Letícia Parreiras Nunes Sousa
Cristina de Mello Gomide Loures
Marcus Vinícius Dias Souza
Ana Cristina Simões e Silva
Luci Maria SantAna Dusse
Abstract: This paper aims to review the diagnosis, epidemiological data, etiology, pathophysiology and progression of Chronic Kidney Disease (CKD), with emphasis on pediatric patients. CKD is defined as a group of structural and functional kidney abnormalities observed for more than three months, which affects patient's health. CKD prevalence in children is lower than in adults, but is associated to cardiovascular diseases and has high mortality and morbidity rates. CKD-affected children have alterations in physical and psychological development, growth retardation and muscle weakness, among other complications which decrease patients’ quality of life. The main causes of CKD in children are congenital anomalies of the kidney and urinary tract, and primary glomerulopathy, especially focal segmental glomerulosclerosis. Some conditions contribute to CKD progression, such as responsiveness to treatment. The knowledge of the pathophysiology of CKD and disease progression mechanisms is important for the early treatment and to predict the clinical evolution, aiming to provide counseling to families and to slow the progression of kidney disease to an end stage.
Subject: Insuficiência renal crônica
Pediatria
Prevalência
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: FAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
MED - DEPARTAMENTO DE PEDIATRIA
Rights: Acesso Aberto
URI: http://hdl.handle.net/1843/40060
Issue Date: 2016
metadata.dc.url.externa: https://www.ijhsr.org/archive_ijhsr_vol.6_issue8.html
metadata.dc.relation.ispartof: International Journal of Health Sciences and Research
Appears in Collections:Artigo de Periódico

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