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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/40188
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dc.creatorRaquel Virgínia Rocha Vilelapt_BR
dc.creatorGregory Dana Bossartpt_BR
dc.creatorJudy A. St. Legerpt_BR
dc.creatorLeslie M. Daltonpt_BR
dc.creatorJohn S. Reifpt_BR
dc.creatorAdam M. Schaeferpt_BR
dc.creatorPeter J. McCarthypt_BR
dc.creatorPatricia A. Fairpt_BR
dc.creatorLeonel Mendozapt_BR
dc.date.accessioned2022-03-17T15:53:42Z-
dc.date.available2022-03-17T15:53:42Z-
dc.date.issued2016-
dc.citation.volume22pt_BR
dc.citation.issue12pt_BR
dc.citation.spage2063pt_BR
dc.citation.epage2069pt_BR
dc.identifier.doihttp://dx.doi.org/10.3201/eid2212.160860pt_BR
dc.identifier.issn1080-6059pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/40188-
dc.description.resumoCutaneous granulomas in dolphins were believed to be caused by Lacazia loboi, which also causes a similar disease in humans. This hypothesis was recently challenged by reports that fungal DNA sequences from dolphins grouped this pathogen with Paracoccidioides brasiliensis. We conducted phylogenetic analysis of fungi from 6 bottlenose dolphins (Tursiops truncatus) with cutaneous granulomas and chains of yeast cells in infected tissues. Kex gene sequences of P. brasiliensis from dolphins showed 100% homology with sequences from cultivated P. brasiliensis, 73% with those of L. loboi, and 93% with those of P. lutzii. Parsimony analysis placed DNA sequences from dolphins within a cluster with human P. brasiliensis strains. This cluster was the sister taxon to P. lutzii and L. loboi. Our molecular data support previous findings and suggest that a novel uncultivated strain of P. brasiliensis restricted to cutaneous lesions in dolphins is probably the cause of lacaziosis/lobomycosis, herein referred to as paracoccidioidomycosis ceti.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofEmerging Infectious Diseasespt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherParacoccidioidespt_BR
dc.subject.otherParacoccidioidomicosept_BR
dc.subject.otherGranulomapt_BR
dc.subject.otherFungospt_BR
dc.subject.otherGolfinhospt_BR
dc.titleCutaneous granulomas in dolphins caused by novel uncultivated Paracoccidioides brasiliensispt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://wwwnc.cdc.gov/eid/articles/issue/22/12/table-of-contentspt_BR
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