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http://hdl.handle.net/1843/40188| Tipo: | Artigo de Periódico |
| Título: | Cutaneous granulomas in dolphins caused by novel uncultivated Paracoccidioides brasiliensis |
| Autor(es): | Raquel Virgínia Rocha Vilela Gregory Dana Bossart Judy A. St. Leger Leslie M. Dalton John S. Reif Adam M. Schaefer Peter J. McCarthy Patricia A. Fair Leonel Mendoza |
| Resumo: | Cutaneous granulomas in dolphins were believed to be caused by Lacazia loboi, which also causes a similar disease in humans. This hypothesis was recently challenged by reports that fungal DNA sequences from dolphins grouped this pathogen with Paracoccidioides brasiliensis. We conducted phylogenetic analysis of fungi from 6 bottlenose dolphins (Tursiops truncatus) with cutaneous granulomas and chains of yeast cells in infected tissues. Kex gene sequences of P. brasiliensis from dolphins showed 100% homology with sequences from cultivated P. brasiliensis, 73% with those of L. loboi, and 93% with those of P. lutzii. Parsimony analysis placed DNA sequences from dolphins within a cluster with human P. brasiliensis strains. This cluster was the sister taxon to P. lutzii and L. loboi. Our molecular data support previous findings and suggest that a novel uncultivated strain of P. brasiliensis restricted to cutaneous lesions in dolphins is probably the cause of lacaziosis/lobomycosis, herein referred to as paracoccidioidomycosis ceti. |
| Assunto: | Paracoccidioides Paracoccidioidomicose Granuloma Fungos Golfinhos |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Instituição: | UFMG |
| Departamento: | FAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS |
| Tipo de Acesso: | Acesso Aberto |
| Identificador DOI: | http://dx.doi.org/10.3201/eid2212.160860 |
| URI: | http://hdl.handle.net/1843/40188 |
| Data do documento: | 2016 |
| metadata.dc.url.externa: | https://wwwnc.cdc.gov/eid/articles/issue/22/12/table-of-contents |
| metadata.dc.relation.ispartof: | Emerging Infectious Diseases |
| Aparece nas coleções: | Artigo de Periódico |
Arquivos associados a este item:
| Arquivo | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| Cutaneous granulomas in dolphins caused by novel uncultivated Paracoccidioides brasiliensis.pdf | 2.13 MB | Adobe PDF | Visualizar/Abrir |
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