Estudo do perfil microbiológico da matéria-prima e do produto acabado de Rhamnus purshiana e Baccharis trimera obtidos de diferentes farmácias de manipulação na cidade de Divinópolis-MG

Abstract

The microbiological quality of raw material used and the handling process of herbal medicines are the key factors to achieve efficiency and safety of the final product. This present study aims to verify the microbiological quality of herbal medicines in handing pharmacies Divinópolis-MG. Four samples from two herbal drugs (Carqueja and Cascara Sagrada, raw material and final product) were collected in four pharmacies in Divinópolis-MG, properly packaged and labeled. These samples were analyzed according to the Pharmacopoeia 5th ed. (2010). The results of the analyzes of total count of mesophilic aerobic pathogens and research revealed that 50% of samples were below the standards for fungi, pharmacy. About pathogenic analyses, one of the establishments presented positive for the bacteria Escherichia coli in samples of raw material and end product of Cascara Sagrada being unfit for human consumption, showing a correlation between contamination of mesophilic aerobic and pathogens. Pharmacy D showed positive results for the sample of E. coli in Cascara Sagrada final product, suggesting that microbial contamination has occurred in the process of handling the product. In view of these results becomes greater oversight as necessary and taking measures to minimize the risk of contamination of these products.