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http://hdl.handle.net/1843/40907| Type: | Artigo de Periódico |
| Title: | Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model |
| Authors: | Luiz Eduardo Moreira Teixeira Bruno Jannotti Pádua André Moreira Castilho Ivana Duval de Araújo Marco Antônio Percope de Andrade Valbert Nascimento Cardoso Simone Odília Antunes Fernandes Jefferson Soares Leal Isabella Kuniko Takenaka |
| Abstract: | Purpose: To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime. Methods: Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3 weeks, scintilographic images were obtained using a gamma chamber. Radioactivity counts were obtained for the region of interest (ROI) on the operated and non-operated paws. Results: Groups A, B, and C showed homogenous distribution of the radiopharmaceutical. Hyper uptake was observed in the operated paw from group D. The ROI target count was higher in the two groups with stainless steel implants. Among the control groups, the count was higher in the stainless steel group. Furthermore, among the contaminated groups, the uptake was higher in the stainless steel group, with a significant difference. The target: non-target ratio was significantly lower in the control and contaminated groups with both titanium and stainless steel, but the comparison between control groups and contaminated groups was only significant in the former. The cpm/g observed after a decay of 48h showed statistically significant differences between groups. Conclusion: Different biomaterials used in implants have an influence on the results of scintigraphy with 99mTc-CFT. |
| Subject: | Biomateriais Infecções periprotéticas Ceftizoxima-99m |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAR - DEPARTAMENTO DE ALIMENTOS FAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS MED - DEPARTAMENTO DE APARELHO LOCOMOTOR MED - DEPARTAMENTO DE CIRURGIA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | 10.1590/s0102-865020180010000002 |
| URI: | http://hdl.handle.net/1843/40907 |
| Issue Date: | Jan-2018 |
| metadata.dc.url.externa: | https://www.scielo.br/j/acb/a/R4FJhBs5vHXdHPLVhk3TYrf/?lang=en# |
| metadata.dc.relation.ispartof: | Acta Cirúrgica Brasileira |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model.pdf | 508.56 kB | Adobe PDF | View/Open |
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