Use este identificador para citar o ir al link de este elemento: http://hdl.handle.net/1843/40919
Tipo: Artigo de Periódico
Título: Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
Autor(es): Priscila Codeiro de Lima Carvalho
Nívea Pereira de Sá
Inayara Cristina Alves Lacerda
Carla Pataro
Luiz Henrique Rosa
Rodrigo Silva Alves
Juliana Pereira Lyon
Carlos Augusto Rosa
Susana Johann
Resumen: Essential oil of cinnamon (Cinnamomum zeylanicum) has been used in medicine and food additives. In the present work, we examined the antifungal activity of essential oil extracted from C. zeylanicum bark against oral opportunistic strains of Candida albicans. In addition, we verified the capability of this essential oil to inhibit fungal adhesion to buccal epithelial cells (BECs), germ tube formation, and proteinase activities. Cinnamon oil presented minimum inhibitory concentration (MIC) values that ranged from 31.2 to 125 µg mL-1 against the isolates of the tested C. albicans strains. Cinnamon essential oil could inhibit the adhesion of C. albicans to BECs for all of the isolates tested in present study. The C. albicans strains showed inhibited proteinase production after treatment with cinnamon oil, based on the MIC values determined for each C. albicans strain. Cinnamon oil was also able to inhibit the germ tube formation of all isolates of C. albicans, with the percentage of inhibition ranging from 44.7 to 82.9%. Our results showed that cinnamon oil presented potent antifungal activity and the ability to inhibit virulence factors of oral pathogenic strains of C. albicans.
Asunto: Plantas medicinais
Canela
Cinnamomum zeylanicum
Óleo essencial
Candida albicans
Idioma: eng
País: Brasil
Editor: Universidade Federal de Minas Gerais
Sigla da Institución: UFMG
Departamento: FAR - DEPARTAMENTO DE ALIMENTOS
ICB - DEPARTAMENTO DE MICROBIOLOGIA
Tipo de acceso: Acesso Aberto
URI: http://hdl.handle.net/1843/40919
Fecha del documento: 2018
metadata.dc.url.externa: https://psmpublishers.org/issues/anti-candida-activity-of-cinnamon-inhibition-of-virulence-factors-of-clinical-strains-of-candida-albicans-by-essential-oil-of-cinnamomum-zeylanicum/
metadata.dc.relation.ispartof: PSM Microbiology
Aparece en las colecciones:Artigo de Periódico



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