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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/41905
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dc.creatorViviane Dias Medeiros Silvapt_BR
dc.creatorMaria Clara Coutinho Macedopt_BR
dc.creatorAmanda Neri dos Santospt_BR
dc.creatorMauro Ramalho Silvapt_BR
dc.creatorRodinei Augustipt_BR
dc.creatorInayara Cristina Alves Lacerdapt_BR
dc.creatorJúlio Onésio Ferreira Melopt_BR
dc.creatorCamila Argenta Fantept_BR
dc.date.accessioned2022-05-23T21:44:00Z-
dc.date.available2022-05-23T21:44:00Z-
dc.date.issued2020-
dc.citation.volume34pt_BR
dc.citation.issue19pt_BR
dc.citation.spage1pt_BR
dc.citation.epage12pt_BR
dc.identifier.doi10.1002/rcm.8883pt_BR
dc.identifier.issn0951-4198pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/41905-
dc.description.resumoRationale The loquat (Eriobotrya japonica Lindl.) is a fruit tree that has been used in Chinese medicine for thousands of years for the treatment of various diseases. The loquat leaf extracts contain several bioactive compounds with antioxidant and antimicrobial properties, and identification of these substances using quick and simple methods has been an analytical trend. Methods The influence of dehydration of loquat leaves (without drying, at 40°C, and at 60°C), the type of solvent (ethanol and methanol), and the method of extraction (shaking and ultrasound) on obtaining extracts containing phenolic compounds and substances with antioxidant and antimicrobial properties was evaluated. The chemical constituents of an extract were identified using paper spray mass spectrometry (PS-MS). Results The extract obtained from the dehydrated leaves at 40°C presented the best results. The extracts obtained from these leaves and with ethanol had the highest values of total phenolics and antioxidant activities, but the methanolic extract subjected to ultrasound had the highest levels of chlorogenic, caffeic, and ellagic acids. All extracts evaluated inhibited the growth of Staphylococcus aureus. Using the PS-MS technique, it was possible to identify the presence of 49 substances such as organic acids, phenolic acids, flavonoids, sugars, quinones, and terpenes. Conclusions In general, extracts of dehydrated leaves at 40°C and extracted with ethanol using ultrasound can be considered a good source of bioactive compounds with potential applications as functional ingredients or additives in the food and pharmaceutical industries. PS-MS was demonstrated to be a simple and ultrafast technique to obtain the chemical profile of the loquat leaf extract.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOSpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE QUÍMICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofRapid Communications in Mass Spectrometrypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectEspectrometria de massaspt_BR
dc.subjectPaper spraypt_BR
dc.subjectEriobotrya japonica Lindl. leavespt_BR
dc.subject.otherEspectrometria de massaspt_BR
dc.subject.otherPaper spraypt_BR
dc.subject.otherEriobotrya japonica Lindl. leavespt_BR
dc.titleBioactive activities and chemical profile characterization using paper spray mass spectrometry of extracts of Eriobotrya japonica Lindl. leavespt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/rcm.8883pt_BR
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