1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/42198
Full metadata record
DC FieldValueLanguage
dc.creatorLetícia Maria de Souza Cordeiropt_BR
dc.creatorÉrica Guilhen Mariopt_BR
dc.creatorCarolina Campos Lima Moreirapt_BR
dc.creatorAngélica Heringer Rodriguespt_BR
dc.creatorSamuel Penna Wannerpt_BR
dc.creatorDanusa Dias Soarespt_BR
dc.creatorLeida Maria Botionpt_BR
dc.creatorAdaliene Versiani Matos Ferreirapt_BR
dc.date.accessioned2022-06-02T18:08:07Z-
dc.date.available2022-06-02T18:08:07Z-
dc.date.issued2019-11-
dc.citation.volume120pt_BR
dc.citation.issue11pt_BR
dc.citation.spage18883pt_BR
dc.citation.epage18893pt_BR
dc.identifier.doihttps://doi.org/10.1002/jcb.29208pt_BR
dc.identifier.issn1097-4644pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/42198-
dc.description.resumoAerobic training induces adaptive responses in skeletal muscles and white adipose tissues, thus facilitating lipid utilization as energy substrates during a physical exercise session. However, the effects of training on cytokines levels and on transcription factors involved in lipid metabolism in muscle and different white adipose depots are still unclear; therefore, these were the aims of the present study. Nineteen adult male Wistar rats were randomly assigned to a trained group or a control, non-trained group. The 10-week training protocol consisted of running on a treadmill, during 1 hour per day, 5 days per week, at 75% of maximum aerobic speed. As expected, trained rats improved their aerobic performance and had augmented citrate synthase activity in the soleus, while the control rats did not. Although body weight was not different between groups, the adiposity index and white adipose depots (ie, epididymal and retroperitoneal) were reduced in trained rats. Training reduced serum concentration of insulin, but failed to change serum concentrations of glucose, triacylglycerol, total cholesterol, and nonesterified fatty acids. Training increased sterol regulatory element-binding protein-1c expression in the gastrocnemius and epididymal adipose tissue, and reduced peroxisome proliferator-activated receptor γ (PPARγ) expression in most of the tissues analyzed. The expression of PPARα and carnitine palmitoyltransferase 1 increased in the gastrocnemius and mesenteric adipose tissue but reduced in epididymal adipose tissue. Triacylglycerol content and tribbles 3 expression reduced in the gastrocnemius of trained rats. Tumor necrosis factor-α and interleukin-6 were increased in all adipose depots evaluated. Collectively, our data indicate that the 10-week aerobic training changed gene expression to improve muscle oxidative metabolism and facilitate lipid degradation in adipose tissues. Our data also highlight the existence of adaptive responses that are distinct between the skeletal muscle and white adipose tissue and between different adipose depots.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentEEF - DEPARTAMENTO DE EDUCAÇÃO FÍSICApt_BR
dc.publisher.departmentENF - DEPARTAMENTO DE NUTRIÇÃOpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Cellular Biochemistrypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCytokinespt_BR
dc.subjectEpididymal tissuept_BR
dc.subjectGastrocnemiuspt_BR
dc.subjectPhysical exercisept_BR
dc.subjectTranscription factorspt_BR
dc.subjectTribbles 3pt_BR
dc.subject.otherCitocinaspt_BR
dc.subject.otherTecido adiposo brancopt_BR
dc.subject.otherExercícios físicospt_BR
dc.subject.otherFatores de transcriçãopt_BR
dc.subject.otherMúsculo esqueléticopt_BR
dc.titleAerobic training induces differential expression of genes involved in lipid metabolism in skeletal muscle and white adipose tissuespt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1002/jcb.29208pt_BR
dc.identifier.orcidhttps://orcid.org/ 0000-0002-4659-1032pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5705-8890pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-2256-8652pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
File Description SizeFormat 
Aerobic training induces differential expression of genes involved in lipid metabolism.pdf825.07 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.