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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/42345
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dc.creatorEmerson Ribeiro Limapt_BR
dc.creatorL. L. S. Cardosopt_BR
dc.creatorAlessandra Rejane Ericsson de Oliveira Xavierpt_BR
dc.creatorAdriana Amaral Carvalhopt_BR
dc.creatorMauro Aparecido de Sousa Xavierpt_BR
dc.creatorHadison Santos Nogueira Curziopt_BR
dc.creatorHigor Rabelo Guedespt_BR
dc.creatorLuciano Freitas Fernandespt_BR
dc.creatorAnna Christina de Almeidapt_BR
dc.creatorElytania Veiga Menezespt_BR
dc.creatorNair Amélia Prates Barretopt_BR
dc.date.accessioned2022-06-08T11:36:06Z-
dc.date.available2022-06-08T11:36:06Z-
dc.date.issued2019-
dc.citation.volume18pt_BR
dc.citation.issue1pt_BR
dc.identifier.doihttp://doi.org/10.4238/GMR18172pt_BR
dc.identifier.issn1676-5680pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/42345-
dc.description.resumoWe characterized six drug-resistant nosocomial isolates of Klebsiella pneumoniae obtained in a hospital located in northern Minas Gerais State, Brazil, by determining their antibiotic sensitivity profiles, detecting the blaKPC genetic marker and examining their clonal relationships. All isolates were found to be extensively drug resistant. A PCR assay was used to confirm the identity of the isolates as K. pneumoniae and assess the blaKPC gene. All isolates tested positive for the blaKPC gene, which is related to carbapenem resistance. The genetic profiles and clonal relationships among the isolates were evaluated by ERIC-PCR. All the isolates were in a single group with two distinct subgroups. Analysis of the genetic diversity among the isolates revealed that five of the six were clones, which suggests cross-transmission in this hospital environment. Five of the patients died from infection. We describe the first detection of KPC-producing K. pneumoniae isolates from a hospital in northern Minas Gerais state.pt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofGenetics and Molecular Researchpt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherBacterias gram-negativaspt_BR
dc.subject.otherInfecções por Bactérias Gram-Negativaspt_BR
dc.titleCharacterization and molecular epidemiology of extensively prevalent nosocomial isolates of drug-resistant klebsiella pneumoniaept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.semanticscholar.org/paper/Research-Article-Characterization-and-molecular-of-Lima-Carvalho/ec00cd9bc4ae45027c20664729630a997b7218capt_BR
dc.identifier.orcidhttps://orcid.org/ 0000-0001-9836-4117pt_BR
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