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http://hdl.handle.net/1843/42544| Type: | Artigo de Periódico |
| Title: | A single session of high-intensity interval exercise increases antioxidants defenses in the hippocampus of Wistar rats |
| Authors: | Camila Melo Luciana Estefani Drumond de Carvalho Ricardo Augusto Leoni de Sousa Hércules Ribeiro Leite Etel Rocha Vieira Daniel Almeida Freitas Bruno Alvarenga Soares Arthur Rocha Gomes Tânia Regina Riul Vanessa Amaral Mendonça Ana Cristina Rodrigues Lacerda Ana Cristina Resende Camargos |
| Abstract: | It is known that a single session of high-intensity interval exercise (HIIE) contributes to the increase of the reactive species of oxygen, accompanied by a greater antioxidant activity. However, it is poorly understood if a single session of HIIE has similar effects on the brain tissue. This study evaluated the effects of a single HIIE on the hippocampal redox status. Sixteen males Wistar rats were allocated into HIIE (n = 8) and control (n = 8) groups. Maximum oxygen consumption (VO2max) was evaluated using a treadmill at 10° inclination in a metabolic chamber. HIIE group was submitted to a single run on the treadmill composed by 10 bouts of high-intensity exercise of 1 min each (85–100% of VO2max), at 28 m/min, 10° inclination, interspersed by 2 min of active recovery, at 10 m/min, with no inclination. Analysis of the redox status at the hippocampus were conducted 24 h after the HIIE session. It was not identified lipid peroxidation in the hippocampus of the HIIE group (Control 1.9 ± 0.31, vs HIIT 2.2 ± 0.53 nmol MDA/mg protein (p > .05). However, the activity of the superoxide dismutase (Control 2.614 ± 0.225 vs HIIT 3.718 ± 0.4589 U/mg protein), and the non-enzymatic total antioxidant capacity (Control 1584 ± 75.88 vs HIIT 1984 ± 137.7 nM FeSO4/mg protein) were enhanced (p < .05) after the exercise session. These results indicate that the antioxidant mechanisms are enhanced even after a single session of HIIE. A single session of HIIE does not induce lipid peroxidation and improves the antioxidant defenses in Wistar rats' hippocampus. |
| Subject: | Exercício físico Exercícios físicos - Aspectos fisiológicos Inflamação Córtex cerebral Ratos Wistar |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | EEF - DEPARTAMENTO DE FISIOTERAPIA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.physbeh.2019.112675 |
| URI: | http://hdl.handle.net/1843/42544 |
| Issue Date: | Nov-2019 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0031938419303099?via%3Dihub |
| metadata.dc.relation.ispartof: | Physiology and Behavior |
| Appears in Collections: | Artigo de Periódico |
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