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http://hdl.handle.net/1843/43908| Type: | Artigo de Periódico |
| Title: | Molecular mechanisms associated with the benefits of variable practice in motor learning |
| Authors: | Tércio Apolinário de Souza Ana Flávia Santos Almeida Natália Lelis Torres Juliana Otoni Parma Grace Schenatto Pereira Moraes Guilherme Menezes Lage |
| Abstract: | Variable practice promotes a higher level of motor learning than constant practice. The glutamate receptors, n-methyl-d-aspartate (NMDA) and alfa-amino-3-hydroxy-5-methyl-4-isoxazolepropionic (AMPA), have been associated with the changes in motor cortex that occur throughout the process of motor learning. Considering that, it is possible that variable practice is more associated with the NMDA and AMPA receptors than constant practice. This study aimed ao investigating the association between the glutamate receptors, NMDA and AMPA, and constant and variable practice schedules. Seventy-eight male mice practiced the rotarod task in a constant or variable scheduling, in two consecutive days (acquisition phase). Learning tests were performed 24 h and 10 days after the end of the acquisition phase. Variable practice was more associated with the NMDA receptor and had a greater AMPA receptor expression than constant practice. The results suggest that the benefits of variable practice are result of both the greater dependency on the NMDA receptor and the greater AMPA receptor expression. |
| Subject: | Aprendizagem motora Exercícios físicos Córtex motor Receptores glutamatérgicos |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | EEF - DEPARTAMENTO DE EDUCAÇÃO FÍSICA ICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1080/00222895.2019.1649997 |
| URI: | http://hdl.handle.net/1843/43908 |
| Issue Date: | 2020 |
| metadata.dc.url.externa: | https://www.tandfonline.com/doi/abs/10.1080/00222895.2019.1649997?journalCode=vjmb20#:~:text=Variable%20practice%20was%20more%20associated,the%20greater%20AMPA%20receptor%20expression. |
| metadata.dc.relation.ispartof: | Journal of Motor Behavior |
| Appears in Collections: | Artigo de Periódico |
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