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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/44291
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dc.creatorDiandra Costa Arantespt_BR
dc.creatorFrancisco Ivison Rodrigues Limeirapt_BR
dc.creatorMonica Yamautipt_BR
dc.creatorAllyson Nogueira Moreirapt_BR
dc.creatorLucas Guimarães Abreupt_BR
dc.creatorCláudia Silami Magalhãespt_BR
dc.date.accessioned2022-08-16T19:11:27Z-
dc.date.available2022-08-16T19:11:27Z-
dc.date.issued2019-
dc.citation.volume17pt_BR
dc.citation.issue5pt_BR
dc.citation.spage403pt_BR
dc.citation.epage412pt_BR
dc.identifier.doi10.3290/j.ohpd.a43272pt_BR
dc.identifier.issn16021622pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/44291-
dc.description.resumoPurpose: To compare the clinical efficacy of toothpastes containing Pro-Argin and NovaMin as dentin hypersensitivity (DH) treatment. Materials and Methods: A systematic review and meta-analysis based on PRISMA was conducted (PROSPERO registration CRD42018095367). Electronic searches were performed in Pubmed, Scopus, Cochrane Library, Web of Science, Virtual Health Library and Open Grey until June 2018, with the terms [pro-argin OR arginine] AND [novamin OR calcium sodium phosphosilicate OR calcium sodium phospho silicate]. Randomised and non-randomised clinical trials comparing DH reduction in adults given Pro-argin-containing toothpastes and NovaMin-containing toothpastes were included. Study selection and quality assessment with Cochrane tool were performed. In the meta-analysis, the comparison between desensitising toothpastes was assessed by standardised mean difference (SMD) with 95% confidence intervals (CI). Certainty of evidence was evaluated with GRADE. Results: Five studies fulfilled the inclusion criteria. In four included studies, a reduction in the DH under tactile stimulus between baseline and post-application times for both toothpastes was demonstrated. Three studies were suitable for meta-analysis. No statistically significant difference between the two toothpastes for DH reduction was observed at immediate (SMD = -1.05, CI = -3.52;1.41), 2-week (SMD = -0.55, CI = -2.59;1.48) and 4-week (SMD = -0.49, CI = -2.78;1.81) follow-up. Certainty of the evidence was very low. Included studies presented a high risk of bias. Conclusions: Pro-argin-containing and NovaMin-containing toothpastes showed effectiveness for DH reduction. No statistically significant difference between the two toothpastes was found. Thus, both can be prescribed to treat DH in adults with equivalent effectiveness up to four weeks.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORApt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofOral Health & Preventive Dentistrypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectPro-arginpt_BR
dc.subjectNovaminpt_BR
dc.subjectToothpastespt_BR
dc.subjectDentin desensitizing agentspt_BR
dc.subjectDentin hypersensitivitypt_BR
dc.subject.otherToothpastespt_BR
dc.subject.otherDentifricespt_BR
dc.subject.otherDentin sensitivitypt_BR
dc.subject.otherDentin desensitizing agentspt_BR
dc.titleComparison of clinical efficacy of pro-argin and novamin toothpastes in relieving dentin hypersensitivity: a systematic review and meta-analysispt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.quintessence-publishing.com/deu/en/article/842236pt_BR
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