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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/44435
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dc.creatorRaquel Gusmão Soarespt_BR
dc.creatorLucyana Conceição Fariaspt_BR
dc.creatorAgna Soares da Silva Menezespt_BR
dc.creatorCarla Silvana de Oliveira e Silvapt_BR
dc.creatorAngeliny Tamiarana Lima Tabosapt_BR
dc.creatorPablo Vinicyus Ferreira Chagaspt_BR
dc.creatorLaís Santiagopt_BR
dc.creatorSergio Henrique Sousa Santospt_BR
dc.creatorAlfredo Maurício Batista de Paulapt_BR
dc.creatorAndré Luiz Sena Guimarãespt_BR
dc.date.accessioned2022-08-22T13:46:22Z-
dc.date.available2022-08-22T13:46:22Z-
dc.date.issued2018-06-15-
dc.citation.volume33pt_BR
dc.citation.spage1813pt_BR
dc.citation.epage1819pt_BR
dc.identifier.doihttps://doi.org/10.1007/s10103-018-2549-ypt_BR
dc.identifier.issn1435-604Xpt_BR
dc.identifier.urihttp://hdl.handle.net/1843/44435-
dc.description.resumoOral squamous cell carcinoma (OSCC) is the most frequent oral malignant neoplasia. As consequence of OSCC treatment, oral mucositis (OM) is one of the most common adverse effects of OSCC treatment. Currently, there is no consensus for OM treatment. The purpose of the current study was to test the combination of red and infrared low-level laser therapy (LLLT) for OM treatment. Primary culture of human fibroblast was performed to identify LLLT dose. After laboratory tests, a two-arm parallel, single-blind, controlled study was conducted. The two arms were group 1, both 660- and 808-nm wavelengths (300 J/cm2, 9 J of total energy, 100 mW, spot size 3 mm2), and group 2, only 660-nm wavelength (300 J/cm2, 9 J of total energy, 100 mW, spot size 3 mm2). Both treatments were performed twice a week. Group 1 presented a reduction of mucositis grade in comparison to group 2. Group 1 also presented reduction of analgesics prescription. But no significant differences between groups 1 and 2 were observed according to the pain scale. In conclusion, the current study demonstrated that a combination of red and infrared at a higher dose (300 J/cm2) reduced both oral mucositis grade and analgesics prescription. The effects of the combination of RT and LLLT are unclear and need more studies.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofLasers in Medical Sciencept_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherBoca - Câncerpt_BR
dc.subject.otherLasers em medicinapt_BR
dc.subject.otherFototerapiapt_BR
dc.subject.otherCarcinoma de células escamosaspt_BR
dc.titleTreatment of mucositis with combined 660- and 808-nm-wavelength low-level laser therapy reduced mucositis grade, pain, and use of analgesics: a parallel, single-blind, two-arm controlled studypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://link.springer.com/article/10.1007/s10103-018-2549-ypt_BR
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