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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/45331
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dc.creatorMaximilian Scheldenpt_BR
dc.creatorWilliam James Nogueira Limapt_BR
dc.creatorEric Will Doerrpt_BR
dc.creatorMartin Wunderlichpt_BR
dc.creatorLars Rehmannpt_BR
dc.creatorJochen Büchspt_BR
dc.creatorLars Regesteinpt_BR
dc.date.accessioned2022-09-20T18:48:38Z-
dc.date.available2022-09-20T18:48:38Z-
dc.date.issued2016-11-14-
dc.citation.volume114pt_BR
dc.citation.issue5pt_BR
dc.citation.spage990pt_BR
dc.citation.epage997pt_BR
dc.identifier.doihttps://doi.org/10.1002/bit.26219pt_BR
dc.identifier.issn1097-0290pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/45331-
dc.description.resumoOne of the most critical parameters in chemical and biochemical processes is the viscosity of the medium. Its impact on mixing, as well as on mass and energy transfer is substantial. An increase of viscosity with reaction time can be caused by the formation of biopolymers like xanthan or by filamentous growth of microorganisms. In either case the properties of fermentation broth are changing and frequently non-Newtonian behavior are observed, resulting in major challenges for the measurement and control of mixing and mass transfer. This study demonstrates a method for the online determination of the viscosity inside a stirred tank reactor. The presented method is based on online measurement of heat transfer capacity from the bulk medium to the jacket of the reactor. To prove the feasibility of the method, fermentations with the xanthan producing bacterium Xanthomonas campestris pv. campestris B100 as model system were performed. Excellent correlation between offline measured apparent viscosity and online determined heat transfer capacity were found. The developed tool should be applicable to any other process with formation of biopolymers and filamentous growth.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofBiotechnology and Bioengineeringpt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectOnline measurementpt_BR
dc.subjectviscositypt_BR
dc.subjectstirred tank bioreactorspt_BR
dc.subject.otherBiorreatorespt_BR
dc.subject.otherViscosidadept_BR
dc.subject.otherBiopolímerospt_BR
dc.subject.otherXanthomonas campestrispt_BR
dc.subject.otherSistemas biológicospt_BR
dc.titleOnline measurement of viscosity for biological systems in stirred tank bioreactorspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1002/bit.26219pt_BR
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