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http://hdl.handle.net/1843/45484| Type: | Artigo de Periódico |
| Title: | In vivo biocompatibility and biomineralization of calcium silicate cements |
| Authors: | Francine Benetti João Eduardo Gomes Filho Juliana Maria de Araujo Lopes Jéssica Barbosa Rogério Jacinto Luciano Tavares Ângelo Cintra |
| Abstract: | A new mineral trioxide aggregate (MTA) material has been developed with a modified composition that requires investigations to support its clinical use. This study evaluated the biocompatibility and biomineralization of this new MTA material and compared it with that of two other MTA cements over time. Tubes containing materials (or empty tubes as controls) were inserted into the subcutaneous tissues of 40 rats. On days 7, 15, 30, 60, and 90, the tubes were removed with the surrounding tissues, which were either stained with haematoxylin and eosin or von Kossa for further analyses or unstained for observation under polarized light. On days 7 and 15, moderate inflammation was observed in most specimens, and the fibrous capsule was thick. On day 30, there was mild inflammation in all groups, and the fibrous capsule was thin. On days 60 and 90, there was mild inflammation in the material groups, while the control group showed no inflammation, although no statistically significant difference between the groups was observed and the fibrous capsule was thin. All material groups showed structures that stained with von Kossa and could be observed under polarized light; this was not found for the control. In conclusion, the new MTA material had biocompatibility and biomineralization properties similar to those of the two existing MTA materials |
| Subject: | Dental cements Dental materials Endodontics Inflammation |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1111/eos.12539 |
| URI: | http://hdl.handle.net/1843/45484 |
| Issue Date: | 1-Jul-2018 |
| metadata.dc.url.externa: | https://onlinelibrary.wiley.com/doi/10.1111/eos.12539 |
| metadata.dc.relation.ispartof: | European Journal of Oral Sciences |
| Appears in Collections: | Artigo de Periódico |
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