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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/45623
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dc.creatorLeopoldo Cosme-Silvapt_BR
dc.creatorFrancine Benettipt_BR
dc.creatorRenan Dal-Fabbropt_BR
dc.creatorJoão Eduardo Gomes Filhopt_BR
dc.creatorVivien Thiemy Sakaipt_BR
dc.creatorLuciano Tavares Ângelo Cintrapt_BR
dc.creatorNathalia Alvarezpt_BR
dc.creatorEdilson Ervolinopt_BR
dc.creatorNaiana Viana Violapt_BR
dc.date.accessioned2022-09-27T19:21:43Z-
dc.date.available2022-09-27T19:21:43Z-
dc.date.issued2019-01-08-
dc.citation.volume29pt_BR
dc.citation.issue03pt_BR
dc.citation.spage352pt_BR
dc.citation.epage360pt_BR
dc.identifier.doihttps://doi.org/10.1111/ipd.12464pt_BR
dc.identifier.issn09607439pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/45623-
dc.description.resumoAim: To evaluate the inflammatory response, biomineralization and production of osteocalcin (OCN), osteopontin (OPN), and bone sialoprotein (BSP) of a new root filling material for primary teeth (Bio-C Pulpecto) compared to MTA. Design: Polyethylene tubes containing Bio-C Pulpecto, MTA, and empty tubes were implanted into the dorsal connective tissue. After 7, 15, 30, 60, and 90 days, the tubes with surrounding tissue were removed and histologically processed to be analysed using haematoxylin and eosin, von Kossa staining, or no staining for observation under polarized light and immunohistochemistry for the detection of OCN, OPN, and BSP. The Kruskal-Wallis test was used followed by Dunn's test. The significance level was set at 5%. Results: The inflammatory response observed with MTA and Bio-C Pulpecto was more exacerbated until the 15th day and decreased from 30 days on. No significant difference was found between control, MTA, and Bio-C Pulpecto (P > 0.05). Bio-C Pulpecto and MTA showed positivity for von Kossa and birefringent to polarized light. The immunolabelling for OCN, OPN, and BSP was more intense for MTA and Bio-C Pulpecto on days 60 and 90 (P > 0.05). Conclusion: Bio-C Pulpecto was biocompatible, induced biomineralization and was immunopositive for osteogenic markers such as OCN, OPN, and BSP, similarly to MTApt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational journal of Paediatric Dentistrypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectBioactivitypt_BR
dc.subjectBiomineralizationpt_BR
dc.subjectPulpectomypt_BR
dc.subjectTooth Primary.pt_BR
dc.subject.otherBiomineralizationpt_BR
dc.subject.otherPulpectomypt_BR
dc.subject.otherTooth deciduouspt_BR
dc.subject.otherInflammationpt_BR
dc.subject.otherOsteocalcinpt_BR
dc.subject.otherOsteopontinpt_BR
dc.titleBiocompatibility and biomineralization ability of bio-c pulpecto. a histological and immunohistochemical studypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/ipd.12464pt_BR
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