1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Evento
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/46348
Full metadata record
DC FieldValueLanguage
dc.creatorRenata Cristina Rezende Macedo do Nascimentopt_BR
dc.creatorJuliana Alvarespt_BR
dc.creatorAugusto Afonso Guerra Júniorpt_BR
dc.creatorFrancisco de Assis Acurciopt_BR
dc.date.accessioned2022-10-19T01:25:25Z-
dc.date.available2022-10-19T01:25:25Z-
dc.date.issued2017-08-22-
dc.citation.issue33pt_BR
dc.citation.spage112pt_BR
dc.citation.epage112pt_BR
dc.identifier.doihttps://doi.org/10.1002/pds.4275pt_BR
dc.identifier.issn1099-1557pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/46348-
dc.description.resumoBackground: Several literature reviews have highlighted the benefits of using statins in the prevention of cardiovascular disease. The scientific evidences support the inclusion of statins in many protocols and the promotion of their use on a global scale. Population-based studies on the use of statins are still scarce, with the main evidence from randomized clinical trials. Knowledge of the profile of medicines use in the real world is essential for improving health care and public policies. Objectives: This study aims to characterize the use of statins in primary health care of the Unified Health System (SUS) in Brazil and assess the associated factors to the statins use. Methods: This is a cross-sectional study of evaluative nature and integrates the National Research of Access, Use and Promotion of Rational Use of Drugs (PNAUM). Interviews were conducted with patients and health professionals through semi-structured questionnaires in SUS primary health care services. Drugs were described by the Brazilian nonproprietary name and classified according to the fifth level of the Anatomical Therapeutic Chemical Index (ATC). Absolute and relative frequencies were used to describe the variables, using the plan of complex sample analysis. For comparison of the groups, the Pearson chisquare test was used. The association between use of statins and sociodemographic variables and indicators of health conditions was assessed by logistic regression model. The variables selected in the univariate models (p-value ≤0.20) were included in the multivariate model, where remained those with p-value <0.05. The quality of model was checked by the Hosmer–Lemeshow test. Results: The prevalence of statins use among drug users was 9.4% in the primary health care services. The average of medicines used per person was 4.1. The most used drugs were simvastatin (90.3% CI 95% 84.2–94.2), atorvastatin (4.7% CI 95% 1.7– 12.4) and rosuvastatin (1.9% CI 95% 0.9–3.9). However, rosuvastatin is not included in the national list of essential medicines. Statins use was significantly associated with age 45–64 years old (OR 2.49), the caucasian race (OR 1.40), presence of metabolic disorders (OR 9.67), diseases of the circulatory system (OR 1.47) and polypharmacy (five or more drugs used) (OR 9.35). Conclusions: The average of medicines used per person and the association between polypharmacy and statins use may be related to inappropriate use of drugs. This study provides elements for the improvement of safe prescription practices and to qualify the use of medicines in the SUS primary health care.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational Conference on Pharmacoepidemiology & Therapeutic Risk Managementpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectEstatinaspt_BR
dc.subjectAtenção Primária à Saúdept_BR
dc.subject.otherEstatinaspt_BR
dc.subject.otherAtenção Primária à Saúdept_BR
dc.titleUse of statins in primary health care – Brazilpt_BR
dc.typeArtigo de Eventopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/full/10.1002/pds.4275pt_BR
Appears in Collections:Artigo de Evento

Files in This Item:
File Description SizeFormat 
Use of Statins in Primary Health Care – Brazil.pdf63.17 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.