Evidências da ozonioterapia no tratamento da lesão cutânea crônica

Abstract

Ozone therapy is a treatment that consists in the use of ozone as a gas or in water or oil conveyed. Its use as a therapeutic agent must be extracted from medical oxygen using equipments. The ozone, in contact with injured tissue, provides an increased release of growth factors that contribute to tissue repair. The objective of this research was to provide recommendations for the use of ozone in the treatment of chronic skin lesion. This study adopted as theoretical referential evidence-based practice and as methodological, referential the integrative review. To this end, we conducted a search for articles in databases: MEDLINE, LILACS CINAHAL, COCHRANE, and IBECS SCIELO having as inclusion criteria primary studies, randomized controlled, nonrandomized controlled and descriptive studies, whose samples were composed of adults with cutaneous injury of any etiology and treatment has been done with topical application of ozone. The total sample were 03 articles, 02 randomized controlled trials and 01 prospective descriptive. All studies considered as endpoint total healing of the wound or lesion size reduction, followed by bactericidal action. Descriptive analysis was made and the Adapted Jadad Scale was applied to check the internal validity of studies, whose scores were mostly below the minimum established for a study of high quality. We conclude that by considering only 01 quality study, it was not possible to establish recommendations for the use of ozone therapy in the treatment of skin lesions.