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http://hdl.handle.net/1843/46854| Tipo: | Artigo de Periódico |
| Título: | Efficient antibacterial nanosponges based on ZnO nanoparticles and doxycycline |
| Autor(es): | Diego Fernando Suárez Peñaranda Ana Paula de Figueiredo Monteiro Daniele Cristina Ferreira Frederico Dias Brandão Klaus Wilhelm Heinrich Krambrock Luzia Valentina Modolo María Esperanza Cortés Segura Ruben Dario Sinisterra Millán |
| Resumen: | Bacterial soft rot is responsible for the loss of about 25% of worldwide production in vegetables and fruits. Efforts have been made to develop an effective nanosponge with the capacity to load and release antibacterial drugs to protect plants. Based on the potential of the ZnO nanoparticles (ZnO–NPs) to achieve this goal, this study synthesized NP via the sol-gel and hydrothermal methods by controlling native defects, such as oxygen vacancies, using thermal treatments and reduced atmospheres. To characterize the ZnO NPs, X-ray diffraction (XRD), Raman spectroscopy, transmission electron microscopy (TEM), optical spectroscopy, electron paramagnetic resonance (EPR), Zeta Potential measurements and surface area with the Brunauer–Emmett–Teller (BET) method were used. The photophysical and photochemical properties via spin trapping method aligned with EPR using UVA light showed a greater formation of electron-hole pairs and hydroxyl radicals for the reduced ZnO NPs when compared with the oxidized ones. Additionally, we found that reduced ZnO-NPs have high effectively against Escherichia coli, Erwinia carotovora and Pantoea sp. bacteria using the photocatalytic effect in the UV range. Moreover, ZnO-NPs loaded with DOX release profile enables the release of DOX within 46 days, where 25% was released during the first 10 h followed by a second delivery phase with an interesting short-term efficacy (< 1 day) against E. carotovora and Pantoea sp. Bacteria. For the first time, it was demonstrated that ZnO-NPs and ZnO-NPs loaded with DOX have efficient UV photocatalytic activities against bacterial soft rot infections. |
| Asunto: | Nanopartículas |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Institución: | UFMG |
| Departamento: | FAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA ICB - DEPARTAMENTO DE BOTÂNICA ICX - DEPARTAMENTO DE FÍSICA ICX - DEPARTAMENTO DE QUÍMICA |
| Tipo de acceso: | Acesso Restrito |
| Identificador DOI: | https://doi.org/10.1016/j.jphotobiol.2017.10.018 |
| URI: | http://hdl.handle.net/1843/46854 |
| Fecha del documento: | 2017 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S101113441730564X |
| metadata.dc.relation.ispartof: | Journal of Photochemistry and Photobiology B: Biology |
| Aparece en las colecciones: | Artigo de Periódico |
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