Continuous flow dynamic kinetic resolution of rac-1-phenylethanol using single packed-bed containing immobilized CAL-B lipase and VOSO4 as racemization catalyst

Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/47137

Type:	Artigo de Periódico
Title:	Continuous flow dynamic kinetic resolution of rac-1-phenylethanol using single packed-bed containing immobilized CAL-B lipase and VOSO4 as racemization catalyst
Authors:	Rodrigo Octavio Mendonça Alves de Souza Amanda Silva de Miranda Raquel A. C. Leão Stefania de Souza Fernanda Cabella Dias Marcus Vinicius Mattos Silva
Abstract:	Herein, we report a method for the continuous flow DKR of rac-1-phenylethanol catalyzed by CAL-B and VOSO4, using a single packed-bed containing both catalysts. Taking advantage of continuous flow techniques to circumvent compatibility issues, the DKR of rac-1-phenylethanol could be performed continuously to give enantiopure (R)-esters with excellent conversions and high productivities.
Subject:	Síntese orgânica Extração por solventes Hidrólise Cromatografia líquida Racemização Candida Síntese assimétrica
language:	eng
metadata.dc.publisher.country:	Brasil
Publisher:	Universidade Federal de Minas Gerais
Publisher Initials:	UFMG
metadata.dc.publisher.department:	ICX - DEPARTAMENTO DE QUÍMICA
Rights:	Acesso Restrito
metadata.dc.identifier.doi:	https://doi.org/10.1039/C7RE00003K
URI:	http://hdl.handle.net/1843/47137
Issue Date:	2017
metadata.dc.url.externa:	https://pubs.rsc.org/en/content/articlelanding/2017/re/c7re00003k#!
metadata.dc.relation.ispartof:	Reaction Chemistry & Engineering
Appears in Collections:	Artigo de Periódico

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